Rodríguez-Reimundes Ezequiel, Soler-Pujol Gervasio, Díaz Carlos H, Dávalos-Michel Mario, Jost Luis J, Laham Gustavo, Vilches Antonio R
Nephrology and Transplantation Section, Department of Medicine, Hospital Universitario CEMIC, Buenos Aires, Argentina.
Clin Transplant. 2014 Mar;28(3):377-82. doi: 10.1111/ctr.12323. Epub 2014 Feb 15.
Travel for transplantation and transplant commercialism have become major issues in the last years, generating a passionate medical, legal, and ethical debate. We evaluated the general characteristics of patients who received a kidney transplant abroad and were subsequently followed in our institution. Then, we carried out a retrospective analysis of travelers' outcomes and compared them with a matched cohort of patients transplanted in our center. Between 1971 and 2008, 58 kidney transplants were performed outside Argentina and were subsequently followed up at our institution. The main destinations were the USA (32.8%), Bolivia (29.3%), and Brazil (17.2%). Deceased donor transplants were the most common (53.4%) followed by unrelated living donors (32.8%). No difference was observed between travelers and controls in terms of one-month and one-yr renal function and one-yr and five-yr graft survival. Travelers had significantly less time on dialysis before transplantation than controls. The major destination among all travelers was the USA, and the main destination for commercial transplants was Bolivia. The destination countries involved in our study and the apparent non-inferiority of travelers graft outcomes differ from those of previous reports.
近年来，移植旅行和移植商业化已成为重大问题，引发了激烈的医学、法律和伦理辩论。我们评估了在国外接受肾移植并随后在我们机构接受随访的患者的一般特征。然后，我们对这些旅行者的结局进行了回顾性分析，并将他们与在我们中心接受移植的匹配队列患者进行了比较。1971年至2008年期间，在阿根廷境外进行了58例肾移植，随后在我们机构进行了随访。主要目的地是美国（32.8%）、玻利维亚（29.3%）和巴西（17.2%）。尸体供体移植最为常见（53.4%），其次是无关活体供体（32.8%）。在移植后1个月和1年的肾功能以及1年和5年的移植物存活率方面，旅行者和对照组之间未观察到差异。旅行者移植前透析的时间明显少于对照组。所有旅行者中的主要目的地是美国，商业移植的主要目的地是玻利维亚。我们研究中涉及的目的地国家以及旅行者移植物结局的明显非劣效性与之前的报告不同。
