University at Albany, State University of New York, Albany, New York.
University at Albany, State University of New York, Albany, New York.
JACC Cardiovasc Interv. 2014 Mar;7(3):276-83. doi: 10.1016/j.jcin.2013.10.020. Epub 2014 Feb 13.
This study sought to determine the utilization and outcomes for radial access for percutaneous coronary intervention (PCI) for ST-segment elevation acute myocardial infarction (STEMI) in common practice.
Radial access for PCI has been studied considerably, but mostly in clinical trials.
All patients undergoing PCI for STEMI in 2009 to 2010 in New York were studied to determine the frequency and the patient-level predictors of radial access. Differences in in-hospital/30-day mortality between radial and femoral access were also studied.
Radial access increased from 4.9% in the first quarter of 2009 to 11.9% in the last quarter of 2010. Significant independent predictors were higher body surface area, non-Hispanic ethnicity, Caucasian race, stable hemodynamic state, ejection fraction <30% and ≥50% onset of STEMI from 12 to 23 h before the index procedure, and peripheral vascular disease. Mortality was not related to access site after adjustment for covariates (for radial vs. femoral access, adjusted odds ratio: 0.86, 95% confidence interval: 0.59 to 1.25), but the radial access site was trending toward lower mortality for the 9 hospitals that used it for more than 10% of their patients (adjusted odds ratio: 0.61, 95% confidence interval: 0.36 to 1.02).
The use of a radial access site for PCI in STEMI patients increased between 2009 and 2010, but was still infrequent in 2010, and was used for lower-risk STEMI patients. There was no significant difference in mortality by access site, but there was a trend toward a mortality advantage for patients with a radial access site among hospitals that used it relatively frequently.
本研究旨在确定在常规实践中经皮冠状动脉介入治疗(PCI)中桡动脉入路用于 ST 段抬高型急性心肌梗死(STEMI)的应用情况和结局。
经桡动脉入路行 PCI 的研究已有很多,但大多是临床试验。
研究了 2009 年至 2010 年期间在纽约接受 STEMI 行 PCI 的所有患者,以确定桡动脉入路的频率和患者水平的预测因素。还研究了桡动脉和股动脉入路的院内/30 天死亡率差异。
桡动脉入路的比例从 2009 年第一季度的 4.9%增加到 2010 年最后一个季度的 11.9%。独立的显著预测因素包括更高的体表面积、非西班牙裔、白种人、稳定的血流动力学状态、射血分数<30%以及 STEMI 从 12 至 23 小时前开始,以及外周血管疾病。调整协变量后,死亡率与入路部位无关(桡动脉与股动脉相比,调整后的优势比:0.86,95%置信区间:0.59 至 1.25),但对于使用桡动脉入路超过 10%患者的 9 家医院,桡动脉入路的趋势是死亡率较低(调整后的优势比:0.61,95%置信区间:0.36 至 1.02)。
2009 年至 2010 年间,STEMI 患者经皮冠状动脉介入治疗中桡动脉入路的应用有所增加,但在 2010 年仍不常见,并且用于风险较低的 STEMI 患者。入路部位死亡率无显著差异,但在使用桡动脉入路较为频繁的医院中,桡动脉入路患者的死亡率呈下降趋势。