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心包积液与巨细胞动脉炎。

Pericardial effusion and giant cell arteritis.

作者信息

Zenone Thierry, Puget Marie

机构信息

Unit of Internal Medicine, Department of Medicine, Centre Hospitalier General, 179 boulevard Marechal Juin, 26953, Valence Cedex 9, France,

出版信息

Rheumatol Int. 2014 Oct;34(10):1465-9. doi: 10.1007/s00296-014-2958-6. Epub 2014 Feb 17.

Abstract

Pericardial effusion in patients with giant cell arteritis has been described in case reports. The exact prevalence of this manifestation is unknown. The objective of this study was to determine the prevalence and characteristics of pericardial effusion in patients with giant cell arteritis. Retrospective data were collected from 114 patients at a single hospital with giant cell arteritis diagnosed between October 1999 and July 2013. Pericardial effusion was found in four patients (3.5 %, 95 % confidence intervals 1-8.7). In three cases, pericardial effusion was present at initial presentation and was asymptomatic. In one case, pericardial effusion was associated with aortitis and diagnosed at 6 months on thoracic CT scan because of relapse of the disease when corticosteroid was reduced. Prognosis was good in all cases. The present study confirms that pericardial effusion could occur in patients with giant cell arteritis. However, pericardial effusion is a rare manifestation of giant cell arteritis. Clinical course of pericardial effusion in the setting of giant cell arteritis is usually benign and rarely symptomatic. Recognition of this manifestation may contribute to early diagnosis of the disease.

摘要

病例报告中已描述了巨细胞动脉炎患者的心包积液情况。这种表现的确切患病率尚不清楚。本研究的目的是确定巨细胞动脉炎患者心包积液的患病率和特征。回顾性收集了1999年10月至2013年7月期间在一家医院确诊为巨细胞动脉炎的114例患者的数据。4例患者发现心包积液(3.5%,95%置信区间1 - 8.7)。3例患者在心包积液初次出现时无症状。1例患者的心包积液与主动脉炎相关,因在减少皮质类固醇用量时疾病复发,于6个月时经胸部CT扫描确诊。所有病例预后良好。本研究证实巨细胞动脉炎患者可能发生心包积液。然而,心包积液是巨细胞动脉炎的一种罕见表现。巨细胞动脉炎患者心包积液的临床病程通常是良性的,很少有症状。认识到这种表现可能有助于疾病的早期诊断。

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