de Lavernhe-Lemaire M C, Beutter P
Service d'Oto-Rhino-Laryngologie, CHU Tours, France.
Arch Int Physiol Biochim. 1987 Nov;95(4):333-40.
In the rat, nicotine bitartrate (100 micrograms/kg) by intraperitoneal route provokes modifications of the brain stem auditory evoked potentials. These changes are complex: a) decrease of the amplitude of waves IV and V, probably by fixation on nicotinic type receptors, neuronal serotonin stores being normal; b) increase of the amplitude of waves I, I' and II, more important when endogenous stores are depleted; c) increase in the latency of these waves when serotonin stores are normal.
在大鼠中，腹腔注射酒石酸尼古丁（100微克/千克）会引起脑干听觉诱发电位的改变。这些变化很复杂：a）IV波和V波振幅降低，可能是由于作用于烟碱型受体，而神经元5-羟色胺储备正常；b）I波、I'波和II波振幅增加，当内源性储备耗尽时更为明显；c）当5-羟色胺储备正常时，这些波的潜伏期延长。
