Doloi Pankaj Kumar, Baruah D K, Goswami S C, Pathak G K
Department of ENT, Gauhati Medical College & Hospital, Guwahati, Assam 781032 India.
Indian J Otolaryngol Head Neck Surg. 2014 Jan;66(Suppl 1):326-8. doi: 10.1007/s12070-011-0299-2. Epub 2011 Aug 28.
Aspergillosis of larynx is very rare. Only a few cases have been reported in medical literature. Larynx is generally involved secondarily by aspergillosis. Only rarely the larynx happens to be the primary site of involvement. The lesions may be confined to the vocal folds or may involve various other sites of the larynx. There is, invariably, certain risk factors which may predispose for fungal infection like immune deficiency condition, use of inhaled or systemic steroids, long and continuous use of antibiotics etc. These lesions may mimic malignancy or a premalignant condition. Awareness of this entity is essential as the management depends on accurate diagnosis. These lesions invariably respond well to antifungal therapy with elimination of risk factors. Here we have reported a case of primary aspergillosis of the larynx without involvement of other part of the airway and without any generalized immune deficit in a 35 year old woman.
喉曲霉菌病非常罕见。医学文献中仅报道过少数病例。喉通常是曲霉菌病的继发受累部位。喉极少成为原发受累部位。病变可能局限于声带,也可能累及喉的其他各个部位。总是存在某些可能易引发真菌感染的危险因素,如免疫缺陷状况、吸入或全身性使用类固醇、长期持续使用抗生素等。这些病变可能类似恶性肿瘤或癌前病变。认识到这一疾病实体至关重要,因为治疗取决于准确诊断。消除危险因素后,这些病变对抗真菌治疗总是反应良好。在此,我们报告了一例35岁女性原发性喉曲霉菌病病例,气道其他部位未受累且无任何全身性免疫缺陷。