Maillet L, Rudigoz R C, Buffin R, Massardier J, Gaucherand P, Huissoud C
Service de gynécologie-obstétrique, hospices civils de Lyon, hôpital de la Croix-Rousse, 104, grande rue de la Croix-Rousse, 69004 Lyon cedex 04, France.
Service de gynécologie-obstétrique, hospices civils de Lyon, hôpital de la Croix-Rousse, 104, grande rue de la Croix-Rousse, 69004 Lyon cedex 04, France; Université Claude-Bernard - Lyon 1, 8, avenue Rockefeller, 69373 Lyon cedex 08, France.
Gynecol Obstet Fertil. 2014 Jun;42(6):383-6. doi: 10.1016/j.gyobfe.2014.01.006. Epub 2014 Feb 15.
Echogenic bowel (EB) represents 1 % of pregnancy and is a risk factor of fetal pathology (infection, cystic fibrosis, aneuploidy). The aim of our study was to determine the fetuses' outcomes with isolated EB.
This is a retrospective study of all patients who presented singleton gestations with a fetal isolated echogenic bowel between 2004 and 2011 in two prenatal diagnosis centers. Search of aneuploidy, infection and cystic fibrosis was systematically proposed as well as an ultrasound monitoring.
On 109 fetus addressed for isolate echogenic bowel five had other signs associated and 74 had a real isolated echogenic bowel (without dilatation, calcification, intrauterine growth restriction). In 30 cases, the EB was not found. Eighty-five percent of the patients had in the first trimester a screening for trisomy 21. None fetus with isolated EB had trisomy, infection or cystic fibrosis. One fetus died in utero and one newborn died of a metabolic disease without digestive repercussions.
The risk of trisomy 21 and the risk to have a serious disease appear low for the fetus with EB. It does not seem necessary to propose a systematic amniocentesis in case of isolated echogenic bowel.
胎儿肠管回声增强(EB)占妊娠病例的1%,是胎儿病变(感染、囊性纤维化、非整倍体)的一个危险因素。我们研究的目的是确定孤立性EB胎儿的结局。
这是一项对2004年至2011年期间在两个产前诊断中心出现单胎妊娠且胎儿孤立性肠管回声增强的所有患者的回顾性研究。系统性地进行了非整倍体、感染和囊性纤维化的检查以及超声监测。
在针对孤立性肠管回声增强的109例胎儿中,5例有其他相关体征,74例有真正的孤立性肠管回声增强(无扩张、钙化、宫内生长受限)。30例中未发现EB。85%的患者在孕早期进行了21三体筛查。无孤立性EB胎儿患有三体、感染或囊性纤维化。1例胎儿死于宫内,1例新生儿死于代谢性疾病,无消化方面的影响。
对于有EB的胎儿,21三体风险和患严重疾病的风险似乎较低。在孤立性肠管回声增强的情况下,似乎没有必要常规进行羊膜腔穿刺术。