Moore D R
University Laboratory of Physiology, Oxford, England.
J Comp Neurol. 1988 Mar 15;269(3):342-54. doi: 10.1002/cne.902690303.
The organization of the auditory brainstem in adult, darkly pigmented ferrets was studied by using the retrograde transport of the lectin wheat germ agglutinin-horseradish peroxidase injected into one inferior colliculus. Retrogradely labelled neurons were found bilaterally in every nucleus of the auditory brainstem. The greatest number of labelled neurons was found in the cochlear nuclei contralateral to the injection site, the ipsilateral medial superior olivary nucleus, both lateral superior olivary nuclei, the ipsilateral ventral nucleus of the lateral lemniscus, both dorsal nuclei of the lateral lemniscus, and the contralateral inferior colliculus. Quantitative assessment of the projections from the cochlear nuclei showed that the number of contralaterally projecting neurons exceeded the number of ipsilaterally projecting neurons by about 50 to one. This ratio remained relatively stable over a wide range of volumes of injected lectin, whereas the absolute number of labelled neurons on each side varied by at least twofold for a constant volume of lectin. These results provide basic data on the ferret auditory system and demonstrate quantitatively some properties of the projections between the cochlear nucleus and the inferior colliculus.
通过将凝集素小麦胚凝集素 - 辣根过氧化物酶逆行运输注入一只成年深色素雪貂的一个下丘，研究了其听觉脑干的组织。在听觉脑干的每个核团中均发现了双侧逆行标记的神经元。在注射部位对侧的耳蜗核、同侧内侧上橄榄核、双侧外侧上橄榄核、同侧外侧丘系腹侧核、双侧外侧丘系背侧核以及对侧下丘中发现的标记神经元数量最多。对来自耳蜗核的投射进行定量评估表明，对侧投射神经元的数量比同侧投射神经元的数量多约50倍。在广泛的注射凝集素体积范围内，该比例保持相对稳定，而对于恒定体积的凝集素，每侧标记神经元的绝对数量至少变化两倍。这些结果提供了关于雪貂听觉系统的基础数据，并定量地证明了耳蜗核与下丘之间投射的一些特性。
