Taha Mahmoud M, Abouhashem Safwat, Abdel-Rahman Ahamad Y
Zagazig University, Faculty of Medicine, Department of Neurosurgery, Zagazig, Egypt.
Turk Neurosurg. 2014;24(1):8-12. doi: 10.5137/1019-5149.JTN.6464-12.1.
The aim of this study is to report the incidence rate of neurosurgical wound infection at our university as well as the predisposing risk factors.
A 2-year hospital prospective study was conducted and included 1110 patients underwent 1181 elective neurosurgical procedures, 50.3% were male. The ages ranged between 4 days and 80 year with mean age of 33.9 ± 19.679. Instrumental spinal devices were applied in 189 (16%) of patients, and 114 (9.7%) underwent shunt surgery, while aneurysmal clips were used in 5 patients only. The mean duration of follow up was 17.46 ± 3.49 months.
41 patients suffered surgical wound infection representing 3.47 % of the patients. Staphylococcus aureus was the commonest organism in 10 (24.39%) patients followed by the E.coli in 5 (12.19%) patients, while the culture revealed no growth in 14 (34.14%) patients. 25 patients have one or more risk factors of wound infection. 28 cases were treated surgically and 13 patients received conservative treatment. 34 wound infections occurred early during hospitalization, while 7 patients had late wound infection. We have two death-related infection from meningitis and sever septicemia.
The neurosurgical wound infection rate is usually low even in developing countries and remains within the accepted rate.
本研究旨在报告我校神经外科手术伤口感染的发生率及其易感风险因素。
进行了一项为期2年的医院前瞻性研究，纳入1110例患者，共进行了1181例择期神经外科手术，其中50.3%为男性。年龄范围在4天至80岁之间，平均年龄为33.9±19.679岁。189例（16%）患者使用了脊柱器械，114例（9.7%）患者接受了分流手术，仅5例患者使用了动脉瘤夹。平均随访时间为17.46±3.49个月。
41例患者发生手术伤口感染，占患者总数的3.47%。金黄色葡萄球菌是最常见的病原体，10例（24.39%）患者感染该菌，其次是大肠杆菌，5例（12.19%）患者感染该菌，14例（34.14%）患者培养结果无细菌生长。25例患者有一个或多个伤口感染风险因素。28例患者接受了手术治疗，13例患者接受了保守治疗。34例伤口感染发生在住院早期，7例患者发生了晚期伤口感染。我们有2例因脑膜炎和严重败血症导致的与感染相关的死亡。
即使在发展中国家，神经外科手术伤口感染率通常也较低，仍在可接受范围内。
