Dagher Walid I, Nasr Viviane G, Patel Anju K, Flis Daniel W, Wein Richard O
Department of Otolaryngology-Head and Neck Surgery, Tufts Medical Center, Boston, Massachusetts.
Department of Anesthesiology, Tufts Medical Center, Boston, Massachusetts.
J Emerg Med. 2014 May;46(5):617-9. doi: 10.1016/j.jemermed.2013.11.092. Epub 2014 Feb 16.
Diffuse idiopathic skeletal hyperostosis (DISH), also known as Forestier's disease, is an ossifying disease of unknown etiology affecting mainly elderly men. It is characterized by hypertrophic anterior vertebral osteophytes with ossification of the spinal anterior longitudinal ligament. Hypertrophic osteophytes can encroach on the aerodigestive tract, leading to significant swallowing and respiratory symptoms.
Acute stridor and respiratory compromise requiring a surgical airway have rarely been reported in patients with DISH. This entity, although rare, should be in the differential diagnosis of acute airway obstruction, particularly in the elderly.
We describe a case of a 91-year-old patient who was transferred to the Emergency Department at Tufts Medical Center with acute stridor. A computed tomography scan of the neck prior to transfer revealed a large anterior cervical osteophyte causing significant airway narrowing. Fiberoptic evaluation confirmed the radiologic finding of near-complete airway obstruction. The patient's respiratory status rapidly deteriorated and he subsequently underwent an emergent awake tracheostomy to secure his airway.
Given the rarity of DISH and the increase in life expectancy, clinicians should be aware of this disease entity and its potential for acute life-threatening respiratory presentation.
弥漫性特发性骨肥厚(DISH),也称为福里斯特尔病,是一种病因不明的骨化性疾病,主要影响老年男性。其特征为椎体前缘骨赘增生并伴有脊柱前纵韧带骨化。肥厚的骨赘可侵犯气道消化道,导致明显的吞咽和呼吸症状。
DISH患者中很少有急性喘鸣和需要手术气道的呼吸功能不全的报道。这种情况虽然罕见,但在急性气道梗阻的鉴别诊断中应予以考虑,尤其是在老年人中。
我们描述了一例91岁患者,因急性喘鸣被转送至塔夫茨医疗中心急诊科。转运前颈部计算机断层扫描显示一个巨大的颈椎前缘骨赘,导致气道明显狭窄。纤维支气管镜评估证实了影像学上近乎完全气道梗阻的发现。患者呼吸状况迅速恶化,随后接受了紧急清醒气管切开术以确保气道通畅。
鉴于DISH的罕见性以及预期寿命的增加,临床医生应了解这种疾病及其急性危及生命的呼吸表现的可能性。