Gopal Gopinath K, Tam Khai L, Krishnan Shibu P, Maddern Ian L
Aged and Extended Care Services, The Queen Elizabeth Hospital, 28 Woodville Road, Woodville, South Australia, Australia 5011.
N Z Med J. 2014 Feb 14;127(1389):81-5.
Bisphosphonates, drug of choice in the treatment of osteoporosis, have been associated with unusual skeletal side effects such as osteonecrosis of jaw and atypical femur fractures in recent years. We report two older patients with bisphosphonate-associated atypical femur fracture from a South Australian tertiary care hospital and a brief discussion of potential diagnostic complexities in this patient population.
双膦酸盐是治疗骨质疏松症的首选药物,近年来已发现其与一些罕见的骨骼副作用有关,如颌骨坏死和非典型股骨骨折。我们报告了南澳大利亚一家三级护理医院的两名老年患者,他们患有双膦酸盐相关的非典型股骨骨折,并对该患者群体潜在的诊断复杂性进行了简要讨论。