Suppr超能文献

[硬腭移植:上睑黏膜移植重建方法]

[Transplants from the hard palate: method for mucosal graft reconstruction of the upper eyelid].

作者信息

Emesz M, Krall E M, Rasp M, Bauer F M, Grabner G, Arlt E M

机构信息

Universitätsaugenklinik Salzburg, Paracelsus Medizinische Privatuniversität, Müllner Hauptstr. 48, 5020, Salzburg, Österreich,

出版信息

Ophthalmologe. 2014 Sep;111(9):853-61. doi: 10.1007/s00347-013-3002-z.

Abstract

BACKGROUND

Mucosal grafts from the hard palate for reconstruction of the posterior lamella of the upper eyelid were compared for three different indications. The plastic reconstruction of the upper eyelid was carried out in patients with symblepharon and upper eyelid entropion following an autoimmune disease, in patients with subtotal or total upper eyelid resection due to a neoplasm and in patients with mucous membrane trauma using autogenous mucosal grafts from the hard palate.

PATIENTS

In this retrospective comparative interventional case series 23 eyes from 19 patients were included in whom upper eyelid reconstruction was undertaken at the University Eye Hospital in Salzburg between 2001 and 2012. Reconstruction with hard palate grafts was performed in 5 eyes following extensive tumor resection, in 5 eyes of 3 patients after autoimmune diseases and in 13 eyes of 11 patients following trauma rehabilitation.

RESULTS

In the total collective of patients who underwent upper eyelid reconstruction with hard palate grafts, no graft rejection or loss of graft occurred. Hard palate grafts are useful for reconstruction after tumor surgery in addition to other techniques in order to achieve good functional and esthetic results. For patients suffering from autoimmune disease (e.g. ocular pemphigus and Stevens-Johnson syndrome) the use of hard palate grafts was found to be equally useful, although results can possibly deteriorate over time due to the underlying disease. Hard palate grafts were shown to be very useful in reconstruction of the upper eyelid for correction of entropium due to symblepharon and distichiasis following thermal and chemical burns.

CONCLUSION

Hard palate grafts are suitable as mucosal grafts replacing conjunctiva in systemic disease and are equally effective in the treatment of traumatic upper eyelid defects - such as defects after tumor surgery.

摘要

背景

比较了硬腭黏膜移植用于上睑后层重建的三种不同适应证。对自身免疫性疾病后出现睑球粘连和上睑内翻的患者、因肿瘤行上睑部分或全部切除的患者以及因黏膜创伤使用硬腭自体黏膜移植的患者进行了上睑整形重建。

患者

在这个回顾性比较干预性病例系列中,纳入了19例患者的23只眼,这些患者于2001年至2012年在萨尔茨堡大学眼科医院接受了上睑重建。5只眼在广泛肿瘤切除后采用硬腭移植进行重建,3例患者中的5只眼在自身免疫性疾病后进行了重建,11例患者中的13只眼在创伤修复后进行了重建。

结果

在接受硬腭移植进行上睑重建的患者总体中,未发生移植排斥或移植丢失。除其他技术外,硬腭移植对于肿瘤手术后的重建很有用,可实现良好的功能和美学效果。对于患有自身免疫性疾病(如眼部天疱疮和史蒂文斯 - 约翰逊综合征)的患者,发现使用硬腭移植同样有用,尽管由于基础疾病,结果可能会随时间恶化。硬腭移植在因睑球粘连和热烧伤及化学烧伤后的双行睫导致的内翻矫正的上睑重建中显示非常有用。

结论

硬腭移植适合作为替代结膜的黏膜移植用于全身性疾病,并且在治疗创伤性上睑缺损(如肿瘤手术后的缺损)方面同样有效。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验