Gendelman Howard E, Balogh Lajos P, Bawa Raj, Bradbury Michelle, Chang Esther H, Chiu Wah, Farokhzad Omid, Foldvari Marianna, Lanza Gregory, Wang Kuan
985880 Nebraska Medical Center, Omaha, NE, 68198-5880,
J Neuroimmune Pharmacol. 2014 Mar;9 Suppl 1:S1-3. doi: 10.1007/s11481-014-9526-4.
The 4th Conference of the American Society for Nanomedicine is being held March 28-30, 2014 at the Universities at Shady Grove, Rockville, Maryland. The meeting's theme is on defining the role of nanomedicines for nervous system diagnostics and disease but balanced by broad and timely topics for nanotechnology. Nanoneuromedicine, as defined by the development of small drug formulations for the diagnosis and treatment of degenerative, inflammatory, infectious, vascular, addictive, behavioral and metabolic disorders of the nervous system, will provide a focus for each of the scientific sessions. This research is interdisciplinary and it's in its infancy. The hurdles that preclude translation from bench to bedside would include its delivery across the blood brain barrier, limiting nervous system toxicities, and improving drug targeting to diseased brain subregions. These all pose challenges. Multidisciplinary works in neuroscience (neurobiology, neurochemistry, neurophysiology, and neuroinflammation), bioimaging, and polymer chemistry to facilitate outcomes for formulation manufacture will be vigorously discussed. How drugs reach sites of action need include neural cell specific subcellular compartments. The ASNM meeting will showcase nanoneuromedicine research from leading investigators of divergent scientific backgrounds who define this new field. It will also serve as an incubator for developing investigators and broad new field discoveries. Welcome to the conference and enjoy!
美国纳米医学学会第四届会议于2014年3月28日至30日在马里兰州罗克维尔市绿荫丛中的大学举行。会议主题是确定纳米医学在神经系统诊断和疾病方面的作用,但也兼顾了纳米技术广泛且及时的主题。纳米神经医学,是通过开发用于诊断和治疗神经系统退行性、炎症性、感染性、血管性、成瘾性、行为性和代谢性疾病的小型药物制剂来定义的,将成为每场科学会议的重点。这项研究是跨学科的,且尚处于起步阶段。阻碍从实验室转化到临床应用的障碍包括药物穿过血脑屏障、限制神经系统毒性以及改善药物对患病脑区的靶向性。这些都构成了挑战。将大力讨论神经科学(神经生物学、神经化学、神经生理学和神经炎症)、生物成像以及高分子化学等多学科领域如何促进制剂制造的成果。药物到达作用部位的方式需要涉及神经细胞特定的亚细胞区室。美国纳米医学学会会议将展示来自不同科学背景的顶尖研究人员的纳米神经医学研究成果,这些研究人员定义了这个新领域。它还将成为培养研究人员和推动新领域广泛发现的摇篮。欢迎参加本次会议,祝心情愉快!