Hayabuchi N, Jingu K, Miyoshi M, Hirata H, Masuda K, Shibuya T, Nishimura J, Komiyama S, Ishii E, Kikuchi M
Dept. of Radiology, Faculty of Med. Kyushu Univ.
Gan No Rinsho. 1988 Apr;34(5):698-704.
Results of treatment of 25 Hodgkin's disease patients at Kyushu University Hospital from 1981 to 1985 were reviewed. Total nodal irradiation or MOPP chemotherapy was used mainly. The actuarial 5-year survival rate, 87.2%, was significantly better than the 41.0% of 61 patients treated between 1966 and 1980 (P less than 0.01). However, 12 of the 24 patients in remission eventually relapsed. To further improve the survival rates of patients with Hodgkin's disease, technical improvements in total nodal irradiation and altering Adriamycin-containing chemotherapy protocol from MOPP chemotherapy are advisable.
回顾了1981年至1985年在九州大学医院对25例霍奇金病患者的治疗结果。主要采用全淋巴结照射或MOPP化疗。精算5年生存率为87.2%，显著高于1966年至1980年治疗的61例患者的41.0%（P<0.01）。然而，24例缓解患者中有12例最终复发。为进一步提高霍奇金病患者的生存率，建议在全淋巴结照射技术上进行改进，并改变含阿霉素的化疗方案，不再采用MOPP化疗。
