Babu Ranjith, Back Adam G, Komisarow Jordan M, Owens Timothy R, Cummings Thomas J, Britz Gavin W
Division of Neurosurgery, Duke University Medical Center, Durham, NC, USA.
Division of Pathology, Department of Surgery, Duke University Medical Center, Durham, NC, USA.
Asian J Neurosurg. 2013 Oct;8(4):183-7. doi: 10.4103/1793-5482.125662.
Pituitary adenomas and Rathke's cleft cysts (RCCs) share a common embryological origin. Occasionally, these two lesions can present within the same patient. We present a case of a 39-year-old male who was found to have a large sellar lesion after complaints of persistent headaches and horizontal nystagmus. Surgical resection revealed components of a RCC co-existing with a pituitary adenoma. A brief review of the literature was performed revealing 38 cases of co-existing Rathke's cleft cysts and pituitary adenomas. Among the cases, the most common symptoms included headache and visual changes. Rathke's cleft cysts and pituitary adenomas are rarely found to co-exist, despite having common embryological origins. We review the existing literature, discuss the common embryology to these two lesions and describe a unique case from our institution of a co-existing Rathke's cleft cyst and pituitary adenoma.
垂体腺瘤和拉克氏囊肿（RCCs）有着共同的胚胎学起源。偶尔，这两种病变可出现在同一患者体内。我们报告一例39岁男性病例，该患者因持续头痛和水平性眼球震颤就诊，检查发现鞍区有一巨大病变。手术切除显示拉克氏囊肿与垂体腺瘤并存。对文献进行简要回顾后发现38例拉克氏囊肿与垂体腺瘤并存的病例。在这些病例中，最常见的症状包括头痛和视力改变。尽管拉克氏囊肿和垂体腺瘤有共同的胚胎学起源，但它们很少同时出现。我们回顾现有文献，讨论这两种病变的共同胚胎学，并描述我们机构中一例拉克氏囊肿与垂体腺瘤并存的独特病例。
