甲状腺结节细胞学诊断中抽吸与非抽吸细针活检的联合应用。
Combination of aspiration and non-aspiration fine needle biopsy for cytological diagnosis of thyroid nodules.
作者信息
Kashi Zahra, Torabizadeh Zhila, Akha Ozra, Yaseri Ali, Shahidi Mohammad Hosein, Mokhtare Marjan
机构信息
Department of Internal Medicine, Imam Khomeini Hospital, Mazandaran University of Medical Sciences, Sari, Iran. ; Traditional and Complementary Medicine Research Center, Mazandaran University of Medical Sciences, Sari, Iran. ; Infertility and reproductive Health Research Center, Babol University of Medical Sciences, Babol, Iran.
Department of Pathology, Imam Khomeini Hospital, Mazandaran University of Medical Sciences, Sari, Iran.
出版信息
Caspian J Intern Med. 2011 Fall;2(4):299-303.
BACKGROUND
Good cytological sample is very important for the cytological diagnosis of thyroid nodules. The aim of this study was to evaluate the adequacy of prepared samples by the combination of aspiration and non- aspiration fine needle biopsy.
METHODS
In this descriptive - analytical study, sampling was done simultaneously for each patient in fine needle aspiration and non-aspiration biopsy. The sufficiency of samples was studied using Mair Scoring System. Wilcoxon Signed Rank test was used for the data analysis.
RESULTS
Three hundred two cases (289 females, 13 males) with the mean age of 43.83±12.9 years were evaluated. Inadequate samples were 31 (10.3%) in fine needle aspiration, 40 (13.2%) in non-aspiration and 13 cases (4.3%) by using two methods together (p=0.0001). The average total score was 6.00±2.17 in fine needle aspiration and 5.76±2.26 in non-aspiration method (p=0.08), and 6.6±1.98 in the combination of the two methods (p<0001 comparing with one method alone).
CONCLUSION
The results show that using both methods simultaneously in each nodule considerably increases the efficiency of samples for cytological diagnosis.
背景
优质的细胞学样本对于甲状腺结节的细胞学诊断非常重要。本研究的目的是通过细针穿刺抽吸活检与非抽吸活检相结合的方法评估所制备样本的充足性。
方法
在这项描述性分析研究中，对每位患者同时进行细针穿刺抽吸活检和非抽吸活检取样。使用迈尔评分系统研究样本的充足性。采用威尔科克森符号秩检验进行数据分析。
结果
共评估了302例患者（289例女性，13例男性），平均年龄为43.83±12.9岁。细针穿刺抽吸活检中样本不足的有31例（10.3%），非抽吸活检中有40例（13.2%），两种方法联合使用时样本不足的有13例（4.3%）（p = 0.0001）。细针穿刺抽吸活检的平均总评分为6.00±2.17，非抽吸活检为5.76±2.26（p = 0.08），两种方法联合使用时平均总评分为6.6±1.98（与单独使用一种方法相比，p<0.001）。
结论
结果表明，在每个结节中同时使用这两种方法可显著提高细胞学诊断样本的效率。
Zotero 插件