Maurice Catherine, Mason Warren P
University Health Network, Toronto, Canada.
Expert Rev Neurother. 2014 Apr;14(4):367-77. doi: 10.1586/14737175.2014.890890. Epub 2014 Feb 19.
Seizures represent a major cause of morbidity in patients diagnosed with brain tumors. Seizures in patients with gliomas are disruptive, impact on quality of life; autonomy; the capacity to operate motor vehicles and opportunities for work. The management of seizures in patients with brain tumors is complex and ideally managed in a multidisciplinary fashion. In addition to antiepileptic drugs, surgery, chemotherapy and radiotherapy have potential roles in the management of a glioma patient with intractable epilepsy. The successful management of seizures in patients with brain tumors is possible, it provides considerable benefits in terms of quality of life and should remain a central goal in patient management.
癫痫发作是诊断为脑肿瘤患者发病的主要原因。胶质瘤患者的癫痫发作具有破坏性,会影响生活质量、自主性、驾驶机动车的能力以及工作机会。脑肿瘤患者癫痫发作的管理很复杂,理想情况下应以多学科方式进行管理。除抗癫痫药物外,手术、化疗和放疗在治疗患有顽固性癫痫的胶质瘤患者中也具有潜在作用。成功管理脑肿瘤患者的癫痫发作是可行的,这在生活质量方面具有相当大的益处,并且应始终是患者管理的核心目标。