Travaglini Grazia, Biagetti Simona, Alfonsi Simona, Bearzi Italo, Marmorale Cristina
Ann Ital Chir. 2013 Sep 3;84(6):S2239253X13021506.
The authors report a case of intra-abdominal synovial-sarcoma of the gastrocolic ligament in a 64-years-old woman hospitalized for a palpable abdominal mass and pain. CT scan detected an intra-abdominal mass extended through the abdominal wall into the soft tissues, causing compression and dislocation of intra-abdominal structures (left liver, gallbladder, pylorus and gastric antrum, duodenal bulb). At its back, it was in contact with the pancreas, the vena cava and the right kidney. Biopsy revealed that the mass was an intra-abdominal synovial-sarcoma. Patient received preoperative chemotherapy. After three chemotherapy cycles the patient was admitted to hospital for anemia. CT-scan revealed mass necrosis and bleeding. After red blood cells transfusions, the patient underwent surgery and the mass was resected. Histopathological study confirmed the diagnosis of biphasic Synovial-Sarcoma. SYT-SSX1/2 fusion molecular assessment was attempted, but it was not possible to evaluate the presence of the t (X, 18) (p11.2; q11.2) traslocation. The patient was discharged in good health and received adjuvant chemotherapy. CT-scan after 18 months showed pulmonary and intra-abdominal relapse of the disease.
Gastrocolic ligament, Intra-Abdominal synovial-sarcoma.
作者报告了一例64岁女性胃结肠韧带腹内滑膜肉瘤病例，该患者因可触及的腹部肿块和疼痛入院。CT扫描发现一个腹内肿块，其延伸穿过腹壁进入软组织，导致腹内结构（左肝、胆囊、幽门和胃窦、十二指肠球部）受压和移位。在肿块后方，它与胰腺、腔静脉和右肾接触。活检显示该肿块为腹内滑膜肉瘤。患者接受了术前化疗。三个化疗周期后，患者因贫血入院。CT扫描显示肿块坏死和出血。输血后，患者接受手术，肿块被切除。组织病理学研究证实为双相滑膜肉瘤诊断。尝试进行SYT-SSX1/2融合分子评估，但无法评估t（X，18）（p11.2；q11.2）易位的存在。患者健康出院并接受辅助化疗。18个月后的CT扫描显示疾病出现肺部和腹内复发。
胃结肠韧带；腹内滑膜肉瘤
