Department of Clinical Radiology, University of Ioannina, Ioannina, Greece.
Asian J Androl. 2014 May-Jun;16(3):493-7. doi: 10.4103/1008-682X.122865.
The usefulness of diffusion-weighted magnetic resonance imaging (DWI) in the evaluation of scrotal pathology has recently been reported. A standard reference of normal testicular apparent diffusion coefficient (ADC) values and their variations with age is necessary when interpreting normal testicular anatomy and pathology. We evaluated 147 normal testes using DWI, including 71 testes from 53 men aged 20-39 years (group 1), 67 testes from 42 men aged 40-69 years (group 2) and nine testes from six men older than 70 years (group 3). DWI was performed along the axial plane, using a single shot, multislice spin-echo planar diffusion pulse sequence and b-values of 0 and 900 s mm-2 . The mean and standard deviation of the ADC values of normal testicular parenchyma were calculated for each age group separately. Analysis of variance (ANOVA) followed by post hoc analysis (Dunnett T3) was used for statistical purposes. The ADC values (× 10-3 mm 2 s-1 ) of normal testicular tissue were different among age groups (group 1: 1.08 ± 0.13; group 2: 1.15 ± 0.15 and group 3: 1.31 ± 0.22). ANOVA revealed differences in mean ADC among age groups (F = 11.391, P < 0.001). Post hoc analysis showed differences between groups 1 and 2 (P = 0.008) and between groups 1 and 3 (P = 0.043), but not between groups 2 and 3 (P = 0.197). Our findings suggest that ADC values of normal testicular tissue increase with advancing age.
扩散加权磁共振成像（DWI）在评估阴囊病变中的作用最近已有报道。在解释正常睾丸解剖结构和病理时，需要有一个正常睾丸表观扩散系数（ADC）值的标准参考，并了解其随年龄的变化。我们使用 DWI 评估了 147 个正常睾丸，包括 53 名 20-39 岁男性（第 1 组）的 71 个睾丸、42 名 40-69 岁男性（第 2 组）的 67 个睾丸和 6 名年龄大于 70 岁男性（第 3 组）的 9 个睾丸。DWI 沿轴位平面进行，使用单次激发、多切片自旋回波平面扩散脉冲序列和 b 值为 0 和 900 s mm-2。分别计算每个年龄组正常睾丸实质的 ADC 值的平均值和标准差。采用方差分析（ANOVA）和事后分析（Dunnett T3）进行统计学分析。正常睾丸组织的 ADC 值（×10-3mm2s-1）在不同年龄组之间存在差异（第 1 组：1.08±0.13；第 2 组：1.15±0.15；第 3 组：1.31±0.22）。ANOVA 显示年龄组之间 ADC 值的平均值存在差异（F=11.391，P<0.001）。事后分析显示第 1 组和第 2 组之间（P=0.008）以及第 1 组和第 3 组之间（P=0.043）存在差异，但第 2 组和第 3 组之间无差异（P=0.197）。我们的研究结果表明，正常睾丸组织的 ADC 值随年龄的增长而增加。
