X 射线荧光 CT 与能谱 CT 的分析比较。
Analytic comparison between X-ray fluorescence CT and K-edge CT.
出版信息
IEEE Trans Biomed Eng. 2014 Mar;61(3):975-85. doi: 10.1109/TBME.2013.2294677.
X-ray fluorescence computed tomography (XFCT) and K-edge computed tomography (CT) are two important modalities to quantify a distribution of gold nanoparticles (GNPs) in a small animal for preclinical studies. It is valuable to determine which modality is more efficient for a given application. In this paper, we report a theoretical analysis in terms of signal-to-noise ratio (SNR) for the two modalities, showing that there is a threshold of GNPs concentration such that XFCT has a better SNR than K-edge CT when GNPs concentration is less than this threshold, vice versa. Numerical tests are performed for XFCT and K-edge CT on two kinds of phantoms with multiple concentration levels and structural features. Experimental results illustrate that XFCT is superior to K-edge CT when contrast concentration is lower than 0.4% which coincides with the theoretical analysis.
X 射线荧光计算机断层扫描（XFCT）和 K 边计算机断层扫描（CT）是两种重要的方法，可用于定量研究小动物体内金纳米颗粒（GNPs）的分布，以便进行临床前研究。确定哪种方法在给定应用中更有效是很有价值的。在本文中，我们报告了这两种方法的信噪比（SNR）的理论分析，结果表明存在一个 GNPs 浓度阈值，当 GNPs 浓度低于该阈值时，XFCT 的 SNR 优于 K 边 CT，反之亦然。针对具有多种浓度水平和结构特征的两种模型进行了 XFCT 和 K 边 CT 的数值测试。实验结果表明，当对比浓度低于 0.4%时，XFCT 的性能优于 K 边 CT，这与理论分析结果一致。
Zotero 插件