Zhagn Bo-Li, Fan Xiao-Hui, Liu Yang, Qu Hai-Bin, Zhang Jun-Hua, Chegn Yi-Yu
Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China.
Department of Chinese Medicine Science and Engineering, Zhejiang University, Hangzhou 310058, China.
Zhongguo Zhong Yao Za Zhi. 2013 Nov;38(22):3797-800.
Secondary development of Chinese Patent Medicine (CPM) is an effective and innovation-driven way for the leaping development of Chinese medicine industry with less investment and faster return. Aim to improving the efficacy, safety and batch-to-batch consistency of CPMs, the theory and methodology for the secondary development of CPMs, mode for cultivating superior CPM, approaches to reforming the pharmaceutical technology and the corresponding core technologies were proposed in this paper, which is summarized as 'One objective, Three analyses, Five definitudes and Seven improvements'.
中成药二次开发是中药产业实现跨越式发展的一条有效且创新驱动的途径,具有投资少、回报快的特点。本文旨在提高中成药的疗效、安全性和批间一致性,提出了中成药二次开发的理论与方法、培育优质中成药的模式、改革制药工艺的途径及相应的核心技术,概括为“一个目标、三个分析、五个明确、七个改进”。