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醋酸阿比特龙用于去势抵抗性前列腺癌的经济学分析

The economics of abiraterone acetate for castration-resistant prostate cancer.

作者信息

Dellis Athanasios, Papatsoris Athanasios G

机构信息

University Department of Urology, Sismanoglio General Hospital, Athens, Greece.

出版信息

Expert Rev Pharmacoecon Outcomes Res. 2014 Apr;14(2):175-9. doi: 10.1586/14737167.2014.891444. Epub 2014 Feb 25.

DOI:10.1586/14737167.2014.891444
PMID:24564607
Abstract

Abiraterone acetate is an oral medication that has recently been granted approval for the treatment of metastatic castration resistant prostate cancer (mCRPC) prior and/or after chemotherapy with docetaxel. In this article we assess the economics of abiraterone acetate in mCRPC. Relevant studies demonstrated that abiraterone acetate had a minimal budget impact on health plans. A relevant advantage was the cost savings due to the lack of chemotherapy-related side effects as well as the ease of administration. The results of cost/benefit comparative studies with other novel agents (i.e. cabazitaxel, enzalutamide, sipuleucel-T) are warranted as well as the close collaboration between urologists and medical oncologists.

摘要

醋酸阿比特龙是一种口服药物,最近已被批准用于在多西他赛化疗之前和/或之后治疗转移性去势抵抗性前列腺癌(mCRPC)。在本文中,我们评估了醋酸阿比特龙治疗mCRPC的经济学情况。相关研究表明,醋酸阿比特龙对健康计划的预算影响极小。一个相关优势是由于缺乏化疗相关副作用以及给药方便而节省了成本。与其他新型药物(即卡巴他赛、恩杂鲁胺、 sipuleucel-T)进行成本/效益比较研究的结果以及泌尿科医生和医学肿瘤学家之间的密切合作是有必要的。

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引用本文的文献

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Cost-effectiveness analyses and cost analyses in castration-resistant prostate cancer: A systematic review.去势抵抗性前列腺癌的成本效益分析和成本分析:系统评价。
PLoS One. 2018 Dec 5;13(12):e0208063. doi: 10.1371/journal.pone.0208063. eCollection 2018.
2
Targeting the androgenic pathway in elderly patients with castration-resistant prostate cancer: A meta-analysis of randomized trials.针对去势抵抗性前列腺癌老年患者的雄激素途径:随机试验的荟萃分析。
Medicine (Baltimore). 2016 Oct;95(43):e4636. doi: 10.1097/MD.0000000000004636.
3
Prognostic value of a computer-aided diagnosis system involving bone scans among men treated with docetaxel for metastatic castration-resistant prostate cancer.
多西他赛治疗转移性去势抵抗性前列腺癌的男性患者中,骨扫描计算机辅助诊断系统的预后价值
BMC Cancer. 2016 Feb 16;16:109. doi: 10.1186/s12885-016-2160-1.
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Emerging perspectives in prostate cancer: Insights from the 4th Asia Pacific Prostate Cancer Conference.前列腺癌的新观点:第四届亚太前列腺癌会议见解
Prostate Int. 2015 Dec;3(Suppl):S1-4. doi: 10.1016/j.prnil.2015.10.014. Epub 2015 Oct 22.
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Is there still a place for docetaxel rechallenge in prostate cancer?多西他赛再次挑战疗法在前列腺癌治疗中仍有立足之地吗?
World J Clin Oncol. 2015 Oct 10;6(5):99-103. doi: 10.5306/wjco.v6.i5.99.
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Nomogram for overall survival of Japanese patients with bone-metastatic prostate cancer.日本骨转移性前列腺癌患者总生存的列线图
BMC Cancer. 2015 May 1;15:338. doi: 10.1186/s12885-015-1330-x.
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A review of rectal toxicity following permanent low dose-rate prostate brachytherapy and the potential value of biodegradable rectal spacers.永久性低剂量率前列腺近距离放射治疗后直肠毒性的综述及可生物降解直肠间隔物的潜在价值。
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