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妊娠类天疱疮伴产后复发:一例报告

Pemphigoid gestationis with postpartum flare-up: a case report.

作者信息

Kucukunal Asli, Altunay Ilknur, Sakiz Damlanur

机构信息

Department of Dermatology, Sisli Etfal Training and Research Hospital, Istanbul, Turkey.

出版信息

J Reprod Med. 2013 Nov-Dec;58(11-12):545-9.

Abstract

BACKGROUND

Pemphigoid gestationis (PG), also known as herpes gestationis, is an uncommon autoimmune blistering disease that almost always occurs in the third trimester of pregnancy. The sudden emergence of the disease, its clinical appearance and the course create great stress on the pregnant woman and the fetus. The disease has been associated with premature delivery and small-for-gestational-age infants. Corticosteroids remain the mainstay of therapy.

CASE

A pregnant woman presented with a diffuse blistering and intensely pruritic urticarial plaques that occurred periumbilically and spread to the rest of the body. We report a well-documented case of PG and an overview of the current understanding of the disease.

CONCLUSION

A multidisciplinary approach for diagnosis, treatment and course of the disease from both dermatologic and gynecologic viewpoints is suggested.

摘要

背景

妊娠类天疱疮(PG),又称妊娠疱疹,是一种罕见的自身免疫性水疱病,几乎总是发生在妊娠晚期。该病的突然出现、临床表现和病程给孕妇和胎儿带来了巨大压力。该病与早产和小于胎龄儿有关。皮质类固醇仍然是主要的治疗方法。

病例

一名孕妇出现弥漫性水疱和强烈瘙痒的荨麻疹斑块,最初出现在脐周,随后蔓延至身体其他部位。我们报告一例有充分记录的妊娠类天疱疮病例,并概述目前对该疾病的认识。

结论

建议从皮肤科和妇科的角度对该病的诊断、治疗和病程采取多学科方法。

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