Fuchs C, Scheer C, Schulz K, Dombrowski F, Brückmann S, Kuhn S-O
Klinik und Poliklinik für Anästhesiologie und Intensivmedizin, Universitätsmedizin Greifswald, Ferdinand-Sauerbruch-Str., 17475, Greifswald, Deutschland,
Anaesthesist. 2014 Mar;63(3):225-30. doi: 10.1007/s00101-014-2297-8. Epub 2014 Feb 27.
The overwhelming postsplenectomy infection syndrome (OPSI) is a fulminant sepsis that is mainly caused by Streptococcus pneumoniae and is characterized by a particular high mortality. Patients whose spleen was removed due to a hematological disease are at special risk. Even after the recommended immunization against Streptococcus pneumoniae 20-30 % of these patients do not develop an adequate level of antibody response. Therefore, this particular group of patients must be trained how to behave in case of fever and need to obtain immediate specific sepsis therapy with antibiotic prophylaxis.
脾切除术后暴发性感染综合征（OPSI）是一种暴发性败血症，主要由肺炎链球菌引起，死亡率特别高。因血液系统疾病而切除脾脏的患者面临特殊风险。即使在接受推荐的肺炎链球菌免疫接种后，这些患者中仍有20%-30%无法产生足够水平的抗体反应。因此，必须对这一特殊患者群体进行培训，使其了解发热时应如何应对，并需要在抗生素预防的情况下立即接受特异性败血症治疗。
