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教学医院与非教学医院腰椎手术后的并发症

Complications after lumbar spine surgery between teaching and nonteaching hospitals.

作者信息

Nandyala Sreeharsha V, Marquez-Lara Alejandro, Fineberg Steven J, Hassanzadeh Hamid, Singh Kern

机构信息

From the Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL.

出版信息

Spine (Phila Pa 1976). 2014 Mar 1;39(5):417-23. doi: 10.1097/BRS.0000000000000149.

Abstract

STUDY DESIGN

Retrospective national database analysis.

OBJECTIVE

A national population-based database was analyzed to characterize the perioperative complications of lumbar spine procedures performed at teaching and nonteaching hospitals.

SUMMARY OF BACKGROUND DATA

Perception biases exist regarding the complications of lumbar spine surgery based upon the hospital teaching environment.

METHODS

Data from the Nationwide Inpatient Sample was queried from 2002-2011. Patients undergoing an anterior lumbar interbody fusion, posterior lumbar interbody fusion, anterior/posterior lumbar fusion, or lumbar decompression to treat lumbar degenerative pathology were identified and separated into cohorts based upon the teaching status of the hospital. Patient demographics, Charlson Comorbidity Index, length of stay, complications, mortality, and costs were assessed.

RESULTS

A total of 658,616 lumbar procedures were identified from 2002-2011, of which 367,875 (55.9%) were performed at teaching hospitals. An older patient population comprised the teaching hospital cohort and demonstrated a greater comorbidity burden than the nonteaching group (Charlson Comorbidity Index 2.90 vs. 2.55; P < 0.001). In addition, the teaching hospital cohort was associated with a significantly greater number of multilevel fusion cases (P < 0.001) and incurred a greater mean length of stay (3.7 vs. 3.0 d; P < 0.001). Patients treated at teaching hospitals demonstrated a significantly greater incidence of postoperative pulmonary embolism, deep vein thrombosis, infection, and neurological complications than the nonteaching cohort (P < 0.001). Overall, there were no significant differences in the mean total hospital costs or mortality between the hospital cohorts. Regression analysis demonstrated that teaching status was not a significant predictor of mortality (OR, 1.02; confidence interval 0.8-1.2; P = 0.8).

CONCLUSION

Patients treated in teaching hospitals for lumbar spine surgery incurred a longer hospitalization and a greater incidence of postoperative complications including pulmonary embolism, deep vein thrombosis, infection, and neurological events. These findings may be explained by an increased complexity of procedures performed at teaching hospitals along with an older and a more comorbid patient population. Despite these differences, the teaching status was not a significant predictor of in-hospital mortality after a lumbar spine surgery.

LEVEL OF EVIDENCE

摘要

研究设计

全国性数据库回顾性分析。

目的

分析一个基于全国人口的数据库,以描述教学医院和非教学医院进行腰椎手术的围手术期并发症情况。

背景数据总结

基于医院教学环境,对于腰椎手术并发症存在认知偏差。

方法

查询2002年至2011年全国住院患者样本数据。确定接受前路腰椎椎间融合术、后路腰椎椎间融合术、前后路腰椎融合术或腰椎减压术以治疗腰椎退行性病变的患者,并根据医院的教学状况将其分为不同队列。评估患者人口统计学特征、查尔森合并症指数、住院时间、并发症、死亡率和费用。

结果

2002年至2011年共确定658,616例腰椎手术,其中367,875例(55.9%)在教学医院进行。教学医院队列患者年龄较大,合并症负担比非教学医院组更重(查尔森合并症指数2.90对2.55;P < 0.001)。此外,教学医院队列的多节段融合病例数量显著更多(P < 0.001),平均住院时间更长(3.7天对3.0天;P < 0.001)。教学医院治疗的患者术后肺栓塞、深静脉血栓形成、感染和神经并发症的发生率显著高于非教学医院队列(P < 0.001)。总体而言,两个医院队列的平均总住院费用或死亡率无显著差异。回归分析表明教学状况不是死亡率的显著预测因素(比值比,1.02;置信区间0.8 - 1.2;P = 0.8)。

结论

在教学医院接受腰椎手术治疗的患者住院时间更长,术后并发症发生率更高,包括肺栓塞、深静脉血栓形成、感染和神经事件。这些发现可能是由于教学医院进行的手术复杂性增加,以及患者年龄更大、合并症更多。尽管存在这些差异,但教学状况不是腰椎手术后院内死亡率的显著预测因素。

证据级别

3级。

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