Rodrigues Ana Luzia, Simões Maria de Lourdes Pessole Biondo
Rev Col Bras Cir. 2013 Nov-Dec;40(6):443-8. doi: 10.1590/s0100-69912013000600004.
To analyze the incidence of surgical site infection when the preoperative skin preparation was performed with 10% povidone-iodine and 0.5% chlorhexidine-alcohol.
We conducted a randomized, longitudinal study based on variables obtained from patients undergoing clean and potentially contaminated operations. Those involved were divided into two groups. In group 1 (G1) we included 102 patients with skin prepared with povidone-iodine, and in group 2 (G2), 103, whose skin was prepared with chlorhexidine. In the third, seventh and 30th postoperative days we evaluated the surgical site, searching for signs of infection.
Data related to clinical profile, such as diabetes mellitus, smoking, alcoholism, haematological data (Hb, VG and leukocytes), age and gender, and the related variables, such as number of days of preoperative hospitalization, shaving, topography of incision, antibiotic prophylaxis and resident participation in the operation were not predisposing factors for surgical site infection. Two patients in G1 and eight in G2 undergoing clean operations had some type of infection (p = 0.1789), five in G1 and three in G2 undergoing potentially contaminated operations had some type of infection (p = 0.7205).
The incidence of surgical site infection in operations classified as clean and as potentially contaminated for which skin preparation was done with 10% povidone-iodine and 0.5% chlorhexidine-alcohol was similar.
分析术前使用10%聚维酮碘和0.5%氯己定酒精进行皮肤准备时手术部位感染的发生率。
我们基于从接受清洁手术和可能污染手术的患者获得的变量进行了一项随机纵向研究。所涉及的患者分为两组。第1组(G1)包括102例用聚维酮碘进行皮肤准备的患者,第2组(G2)包括103例用氯己定进行皮肤准备的患者。在术后第3天、第7天和第30天,我们评估手术部位,寻找感染迹象。
与临床特征相关的数据,如糖尿病、吸烟、酗酒、血液学数据(血红蛋白、血细胞比容和白细胞)、年龄和性别,以及相关变量,如术前住院天数、剃毛、切口部位、抗生素预防和住院医师参与手术情况,均不是手术部位感染的易感因素。G1组中2例接受清洁手术的患者和G2组中8例接受清洁手术的患者发生了某种类型的感染(p = 0.1789),G1组中5例接受可能污染手术的患者和G2组中3例接受可能污染手术的患者发生了某种类型的感染(p = 0.7205)。
对于分类为清洁手术和可能污染手术且术前使用10%聚维酮碘和0.5%氯己定酒精进行皮肤准备的手术,手术部位感染的发生率相似。