Hashemi A, Tefagh S, Seifadini A, Moghimi M
Department of Pediatrics, Hematology, Oncology and Genetic Research Center, Shahid Sadoughi University of Medical Sciences Health Services, Yazd, Iran.
MD, Hematology, Oncology and Genetics Research Center, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran.
Iran J Ped Hematol Oncol. 2013;3(3):135-7. Epub 2013 Jul 22.
Infantile Fibrosarcoma is a rare soft tissue tumor in infants and children mostly located in extremities. An infantile and adult form has similar histopathological patterns but survival prognosis is much better in infantile form. Recurrence of infantile fibrosarcoma is common but the rates of metastasis are less than 10 percent in children younger than five Years and 50 percent in children more than 10 years old.
In this case report, we presented a nine years girl with a relapsing mass in her left hand. The pathologic findings showed sheets of spindle-shaped cells with suggested diagnose of infantile fibrosarcoma. She was successfully treated with combination of surgery and chemotherapy with a good outcome.
Infantile fibrosarcoma is a differential diagnose of soft tissue mass in infants and children. It has a good prognosis and distant metastasis is uncommon. Choice of treatment is surgery but chemotherapy and radiotherapy were useful in decrease metastasis.
婴儿纤维肉瘤是婴幼儿罕见的软组织肿瘤，多位于四肢。婴儿型和成人型具有相似的组织病理学模式，但婴儿型的生存预后要好得多。婴儿纤维肉瘤复发常见，但5岁以下儿童转移率低于10%，10岁以上儿童转移率为50%。
在本病例报告中，我们介绍了一名9岁女孩，其左手有复发性肿块。病理结果显示为成片的梭形细胞，提示诊断为婴儿纤维肉瘤。她通过手术和化疗联合治疗获得成功，预后良好。
婴儿纤维肉瘤是婴幼儿软组织肿块的鉴别诊断之一。其预后良好，远处转移不常见。治疗选择是手术，但化疗和放疗有助于减少转移。
