Chen Lin, Xi Hongqing, Shen Weisong
Department of General Surgery, Chinese PLA General Hospital, Beijing 100853, China.
Zhonghua Wei Chang Wai Ke Za Zhi. 2014 Feb;17(2):101-4.
Gastric cancer with liver metastasis (GCLM) is the leading cause of death in patients with advanced gastric cancer. Multiple metastasis was common in GCLM and usually complicated with lesions outside the liver, especially peritoneal metastasis. Most of liver metastasis lesions could not be resected radically. Currently, main treatments for GCLM included radical operation, palliative resection of gastric cancer, ablation of metastatic lesions, intervention and systemic chemotherapy. Based on the current progress in the treatment for GCLM and our clinical experience, the general status of patients, the type of gastric cancer and the degree of liver metastasis should be analyzed, and a cooperative multidisciplinary team (MDT) should be applied to conduct and to choose active and suitable comprehensive treatment for GCLM patients based on individualized therapy principle.
伴有肝转移的胃癌(GCLM)是晚期胃癌患者死亡的主要原因。多发转移在GCLM中很常见,且常合并肝外病变,尤其是腹膜转移。大多数肝转移病灶无法根治性切除。目前,GCLM的主要治疗方法包括根治性手术、胃癌姑息性切除、转移病灶消融、介入治疗和全身化疗。基于目前GCLM治疗的进展以及我们的临床经验,应分析患者的一般状况、胃癌类型和肝转移程度,并应用多学科协作团队(MDT),根据个体化治疗原则,为GCLM患者开展并选择积极合适的综合治疗。