缺乏生理刺激会导致神经末梢的蛋白水解活性降低。
Lack of physiological stimulation induces decreased proteolytic activity in nerve terminals.
作者信息
Gustavsson S, Karlsson J O
机构信息
Institute of Neurobiology, University of Göteborg, Sweden.
出版信息
Neurochem Res. 1988 Jul;13(7):633-5. doi: 10.1007/BF00973280.
PMID:2457820
Abstract
The effect of optic nerve transsection on proteolytic degradation of axonally transported proteins in the superior colliculus of the rabbit was studied. Proteolysis of labeled proteins was determined in vitro in small pieces of the superior colliculus. Within 2 hours after sectioning the optic nerve there was a decreased degradation of slowly transported labeled proteins in the nerve terminals in the superior colliculus.
摘要
研究了视神经横断对兔上丘中轴突运输蛋白的蛋白水解降解的影响。通过对上丘小块组织进行体外测定来确定标记蛋白的蛋白水解情况。视神经横断后2小时内，上丘神经末梢中缓慢运输的标记蛋白的降解减少。
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