Color vision deficiency, most of the time remains an unnoticed problem; even many doctors/health professionals do not know the severity of their color vision deficiency and their disability. Some common difficulties reported by medical practitioners and students of health sciences were in recognizing- widespread body color changes (pallor, cyanosis, icterus, rashes, erythema of skin), colorful charts, slides, test-strips of blood and urine, body products: blood or bile in urine, faeces, sputum, vomitus, microscopy, oral and throat lesions, titration end-points, tissue identification (surgery) etc. The present study was undertaken to evaluate the presence of congenital color vision deficiency among the students of health sciences. The study was carried out among the medical and dental male students of Nepal Medical College and Teaching Hospital (n = 215) from November 2, 2012 to December 4, 2012 with the help of Ishihara chart which was shown to all male participants and were asked to read the impressions in the color chart. The impressions perceived by a person with normal color vision were different from the impressions perceived by a person with color vision deficiency. After careful screening, it was noted that among the study population (n = 215), 12 were color deficient (5.58% of our study population). Among them, one could not appreciate color (total color blindness according to the chart used), protanomaly was detected in 1, deuteranomaly in 3 and deuteranopia in 7 volunteers. Students of health sciences must be made aware of their congenital color vision deficiency and its effects on their work. Screening enables the students and later the health professionals to become aware of limitations in their powers of observation and devise ways of overcoming them. The patient is protected from harm and legal action may be avoided when the health professional have adapted their practice to their deficiency. Medical/ dental students and health professionals must be screened for color vision deficiency and advised about it, so that they can take special care in clinical practice.