Stagi Stefano, Losi Stefania, Chiarelli Francesco, de Martino Maurizio, Falcini Fernanda
Department of Health Sciences, University of Florence, Anna Meyer Children's University Hospital, Florence, Italy.
Ital J Pediatr. 2014 Feb 28;40(1):24. doi: 10.1186/1824-7288-40-24.
We describe a girl with Turner syndrome, a genetic disorder of the X chromosome in a phenotypic female at increased risk of autoimmune and immunological diseases, who developed Kawasaki disease at the age of four years. Given the possible relationship between these two disorders, we recommend suspecting Kawasaki disease in patients with Turner syndrome who present with persistent fever of unknown origin and who are not responsive to antibiotic therapy. Attention should be given to this phenomenon, as patients with Turner syndrome are themselves at higher risk of cardiovascular defects. Further studies are needed to better clarify this issue.
我们描述了一名患有特纳综合征的女孩，特纳综合征是一种发生在表型为女性的X染色体遗传性疾病，这类患者患自身免疫性和免疫性疾病的风险增加，该女孩在4岁时患上了川崎病。鉴于这两种疾病之间可能存在的关联，我们建议对于患有特纳综合征且出现不明原因持续发热且对抗生素治疗无反应的患者，应怀疑其患有川崎病。应关注这一现象，因为特纳综合征患者本身患心血管缺陷的风险更高。需要进一步研究以更好地阐明这个问题。
