Major Michael P, Saltaji Humam, El-Hakim Hamdy, Witmans Manisha, Major Paul, Flores-Mir Carlos
Dr. Michael P. Major is an assistant clinical professor and the director, Inter-disciplinary Airway Research Clinic, Division of Orthodontics, School of Dentistry, Faculty of Medicine and Dentistry, University of Alberta, 5-476 Edmonton Clinic Health Academy, 11405-87 Ave., Edmonton, Alberta, Canada T6G 1C9,
J Am Dent Assoc. 2014 Mar;145(3):247-54. doi: 10.14219/jada.2013.31.
Adenoid hypertrophy may cause sleep-disordered breathing and altered craniofacial growth. The authors conducted a study to gauge the accuracy of alternative tests compared with nasoendoscopy (reference standard) for screening adenoid hypertrophy.
The authors conducted a systematic review that included searches of electronic databases, hand searches of bibliographies of relevant articles and gray literature searches. They included all articles in which an alternative test was compared with nasoendoscopy in children with suspected nasal or nasopharyngeal airway obstruction.
The authors identified seven articles that were of poor to good quality. They identified the following alternative tests: multirow detector computed tomography (sensitivity, 92 percent; specificity, 97 percent), videofluoroscopy (sensitivity, 100 percent; specificity, 90 percent), rhinomanometry with decongestant (sensitivity, 83 percent; specificity, 83 percent) and clinical examination (sensitivity, 22 percent; specificity, 88 percent). Lateral cephalograms tended to have good to fair sensitivity (typically 61-75 percent) and poor specificity (41-55 percent) when adenoid size was evaluated but excellent to good specificity when airway patency was evaluated (68-96 percent).
No ideal tool exists for dentists to screen adenoid hypertrophy, owing to access constraints, radiation concerns and suboptimal diagnostic accuracy. Research is needed to identify a low-risk, easily acceptable, highly valid diagnostic screening tool.
Although lateral cephalograms (which have good to fair sensitivity) and a thorough medical history (which has good specificity) are imperfect individually, when they are used together, they can compensate for each others weaknesses. This combined approach is the best tool available to dentists for screening adenoid hypertrophy.
腺样体肥大可能导致睡眠呼吸紊乱和颅面生长改变。作者开展了一项研究,以评估与鼻内镜检查(参考标准)相比,其他检查用于筛查腺样体肥大的准确性。
作者进行了一项系统评价,包括检索电子数据库、手工检索相关文章的参考文献以及灰色文献检索。纳入所有将疑似鼻或鼻咽气道阻塞患儿的其他检查与鼻内镜检查进行比较的文章。
作者确定了7篇质量从差到好的文章。他们确定了以下其他检查:多排探测器计算机断层扫描(敏感性为92%;特异性为97%)、视频荧光透视检查(敏感性为100%;特异性为90%)、使用减充血剂的鼻阻力测量法(敏感性为83%;特异性为83%)以及临床检查(敏感性为22%;特异性为88%)。在评估腺样体大小时,头颅侧位片的敏感性通常较好至中等(通常为61%-75%),特异性较差(41%-55%),但在评估气道通畅性时,特异性较好至极佳(68%-96%)。
由于存在获取受限、辐射问题和诊断准确性欠佳等情况,不存在供牙医筛查腺样体肥大的理想工具。需要开展研究以确定一种低风险、易于接受且高度有效的诊断筛查工具。
尽管头颅侧位片(敏感性较好至中等)和详尽的病史(特异性较好)单独使用时并不完美,但两者结合使用时可相互弥补不足。这种联合方法是牙医筛查腺样体肥大可用的最佳工具。