Morong S, Benoist L B L, Ravesloot M J L, Laman D M, de Vries N
Department of Otolaryngology, Sint Lucas Andreas Hospital, Jan Tooropstraat 164, 1006 AE, Amsterdam, The Netherlands,
Sleep Breath. 2014 Dec;18(4):851-6. doi: 10.1007/s11325-014-0955-3. Epub 2014 Mar 1.
The aims of this study were to determine the prevalence of positional obstructive sleep apnea (POSA) in patients undergoing bariatric surgery and to evaluate the effect of weight loss brought about by bariatric surgery on POSA. Furthermore, the authors investigated whether body mass index (BMI), neck circumference, apnea-hypopnea index (AHI), and age are predictors for POSA.
A retrospective cohort study was conducted with data collected from patients who were screened for OSA pre-bariatric surgery and completed a follow-up polysomnography post bariatric surgery from August 2008 to November 2012. Descriptive statistics were used to characterize the prevalence of POSA patients, and the Mann-Whitney and Wilcoxon signed-rank tests were used to examine differences between the POSA and non-POSA groups. A logistic regression model was used to determine predictors for POSA.
Thirty-four percent of patients had POSA, which is significantly lower (p<0.001) than in the general population. BMI, neck circumference, and AHI were significantly lower in POSA patients. AHI was the only significant independent predictor for POSA. Of the 91 patients analyzed following bariatric surgery, 35.2% (n=32) no longer had OSA.
The prevalence of POSA in patients undergoing bariatric surgery is significantly lower than the prevalence noted in the general population. A low AHI was shown to be the only significant independent predictor for the presence of POSA.
本研究的目的是确定接受减肥手术患者中体位性阻塞性睡眠呼吸暂停(POSA)的患病率,并评估减肥手术带来的体重减轻对POSA的影响。此外,作者还研究了体重指数(BMI)、颈围、呼吸暂停低通气指数(AHI)和年龄是否为POSA的预测因素。
进行一项回顾性队列研究,收集2008年8月至2012年11月期间在减肥手术前接受阻塞性睡眠呼吸暂停(OSA)筛查并在减肥手术后完成随访多导睡眠图检查的患者的数据。使用描述性统计来描述POSA患者的患病率,并使用曼-惠特尼检验和威尔科克森符号秩检验来检查POSA组和非POSA组之间的差异。使用逻辑回归模型来确定POSA的预测因素。
34%的患者患有POSA,这显著低于(p<0.001)普通人群。POSA患者的BMI、颈围和AHI显著更低。AHI是POSA唯一显著的独立预测因素。在减肥手术后分析的91例患者中,35.2%(n=32)不再患有OSA。
接受减肥手术患者中POSA的患病率显著低于普通人群中观察到的患病率。低AHI被证明是POSA存在的唯一显著独立预测因素。