Dotis John, Printza Nikoleta, Stabouli Stella, Papachristou Fotios
Aristotle University of Thessaloniki, 1st Department of Pediatrics, Hippokratio Hospital, Thessaloniki, Greece.
Perit Dial Int. 2015 Jan-Feb;35(1):26-30. doi: 10.3747/pdi.2013.00138. Epub 2014 Mar 1.
Kocuria species are found in the environment and on human skin. These micro-organisms are generally considered to be nonpathogenic saprophytes, rarely causing infection. However, the peritoneum has been reported to be a site of Kocuria infection. We reviewed all cases of peritonitis in peritoneal dialysis (PD) patients caused by Kocuria species that were reported in the worldwide literature. In total, 12 episodes of Kocuria species peritonitis have been reported in 9 PD patients. The median age of the patients was 62 years (range: 8 - 78 years). In the reported episodes, 4 different Kocuria species were isolated, with K. varians being the predominant species (41.7%). The most common initial symptom was abdominal pain (83.3%), followed by turbid effluent (75%) and fever (33.3%). Intraperitoneal first-generation cephalosporins and glycopeptides were the most-used antibiotics, with first-generation cephalosporins being more often preferred as first-line therapy. The median duration of treatment was 14 days, and in 2 episodes, the Tenckhoff catheter was removed. Although Kocuria peritonitis in PD patients is rare, it should be promptly treated because relapses can occur, especially with K. varians episodes.
考克氏菌属存在于环境和人体皮肤上。这些微生物通常被认为是无致病性的腐生菌，很少引起感染。然而，据报道腹膜是考克氏菌感染的一个部位。我们回顾了全球文献中报道的所有由考克氏菌属引起的腹膜透析（PD）患者腹膜炎病例。共有9例PD患者发生了12次考克氏菌属腹膜炎发作。患者的中位年龄为62岁（范围：8 - 78岁）。在报道的发作中，分离出了4种不同的考克氏菌属，其中变异考克氏菌是主要菌种（41.7%）。最常见的初始症状是腹痛（83.3%），其次是腹水浑浊（75%）和发热（33.3%）。腹腔内第一代头孢菌素和糖肽类是最常用的抗生素，第一代头孢菌素更常被首选作为一线治疗。中位治疗持续时间为14天，有2次发作时拔除了Tenckhoff导管。虽然PD患者的考克氏菌属腹膜炎很少见，但应及时治疗，因为可能会复发，尤其是变异考克氏菌发作时。
