Department of Pharmacy, College of Pharmacy, CHA University, Gyeonggi-do, 463-840, Republic of Korea,
J Microbiol. 2014 Mar;52(3):185-7. doi: 10.1007/s12275-014-4088-y.
The special issue of Journal of Microbiology contains six reviews dealing with cutting edge research achievements in the fields of molecular microbiology focusing on antibacterial research. In a more specific sense, this special issue helps outline the progress of 21(st)-century basic molecular microbiology that can encompass related disciplines regarding a variety of interactions involving bacteria during bacterial pathogenesis and their control: sociomicrobiology (interaction between bacteria), immunology (interaction between bacteria and their hosts), and bacteriophage (phage) virology (interaction between bacteria and their parasites). Recent advancements have rapidly been made in our understanding of the real situation regarding polymicrobial interactions during bacterial infection and in non-mammalian host infection models to uncover the molecular mechanisms of host-bacteria interactions, which will complement our growing knowledge about immune responses toward bacterial and environmental elicitors. Moreover, much attention has recently been paid to phages and phage products as potential antibacterial therapeutics in the era of antibiotic resistance. Below, I summarize the individual contributions in these distinct categories.
《微生物学杂志》特刊包含六篇综述,涉及分子微生物学领域的前沿研究成果,重点关注抗菌研究。更具体地说,本特刊有助于概述 21 世纪基础分子微生物学的进展,涵盖与细菌发病机制及其控制过程中涉及细菌的各种相互作用有关的相关学科:社会微生物学(细菌间相互作用)、免疫学(细菌与其宿主间的相互作用)和噬菌体病毒学(细菌与其寄生虫间的相互作用)。我们对细菌感染过程中多微生物相互作用的实际情况以及非哺乳动物宿主感染模型有了更深入的了解,从而揭示了宿主-细菌相互作用的分子机制,这将补充我们对细菌和环境激发因子免疫反应的不断增长的认识。此外,在抗生素耐药性时代,噬菌体及其产物作为潜在的抗菌治疗药物受到了广泛关注。下面,我总结了这些不同类别中的各个贡献。