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用于定量医学诊断应用的红外成像中的运动跟踪

Motion tracking in infrared imaging for quantitative medical diagnostic applications.

作者信息

Cheng Tze-Yuan, Herman Cila

机构信息

Department of Mechanical Engineering, Johns Hopkins University, 3400 N. Charles Street, Baltimore, MD 21218-2682, USA.

出版信息

Infrared Phys Technol. 2014 Jan;62:70-80. doi: 10.1016/j.infrared.2013.10.009.

DOI:10.1016/j.infrared.2013.10.009
PMID:24587692
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3935328/
Abstract

In medical applications, infrared (IR) thermography is used to detect and examine the thermal signature of skin abnormalities by quantitatively analyzing skin temperature in steady state conditions or its evolution over time, captured in an image sequence. However, during the image acquisition period, the involuntary movements of the patient are unavoidable, and such movements will undermine the accuracy of temperature measurement for any particular location on the skin. In this study, a tracking approach using a template-based algorithm is proposed, to follow the involuntary motion of the subject in the IR image sequence. The motion tacking will allow to associate a temperature evolution to each spatial location on the body while the body moves relative to the image frame. The affine transformation model is adopted to estimate the motion parameters of the template image. The Lucas-Kanade algorithm is applied to search for the optimized parameters of the affine transformation. A weighting mask is incorporated into the algorithm to ensure its tracking robustness. To evaluate the feasibility of the tracking approach, two sets of IR image sequences with random in-plane motion were tested in our experiments. A steady-state (no heating or cooling) IR image sequence in which the skin temperature is in equilibrium with the environment was considered first. The thermal recovery IR image sequence, acquired when the skin is recovering from 60-s cooling, was the second case analyzed. By proper selection of the template image along with template update, satisfactory tracking results were obtained for both IR image sequences. The achieved tracking accuracies are promising in terms of satisfying the demands imposed by clinical applications of IR thermography.

摘要

在医学应用中,红外热成像技术用于通过在稳态条件下定量分析皮肤温度或其随时间的变化(这些信息捕捉在图像序列中)来检测和检查皮肤异常的热特征。然而,在图像采集期间,患者的不自主运动是不可避免的,并且这种运动会破坏对皮肤上任何特定位置的温度测量准确性。在本研究中,提出了一种使用基于模板算法的跟踪方法,以跟踪红外图像序列中受试者的不自主运动。运动跟踪将允许在身体相对于图像帧移动时,将温度变化与身体上的每个空间位置相关联。采用仿射变换模型来估计模板图像的运动参数。应用卢卡斯 - 卡纳德算法来搜索仿射变换的优化参数。在算法中加入加权掩码以确保其跟踪鲁棒性。为了评估跟踪方法的可行性,在我们的实验中测试了两组具有随机平面内运动的红外图像序列。首先考虑了一个稳态(无加热或冷却)红外图像序列,其中皮肤温度与环境处于平衡状态。第二种分析的情况是热恢复红外图像序列,它是在皮肤从60秒冷却中恢复时获取的。通过适当选择模板图像以及模板更新,对于这两个红外图像序列都获得了令人满意的跟踪结果。就满足红外热成像临床应用的要求而言,所实现的跟踪精度很有前景。

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本文引用的文献

1
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Proc SPIE Int Soc Opt Eng. 2013 Mar 13;8669. doi: 10.1117/12.2000569.
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Emerging technologies for the detection of melanoma: achieving better outcomes.新兴技术在黑色素瘤检测中的应用:实现更好的结果。
Clin Cosmet Investig Dermatol. 2012;5:195-212. doi: 10.2147/CCID.S27902. Epub 2012 Nov 12.
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Quantitative visualization and detection of skin cancer using dynamic thermal imaging.使用动态热成像对皮肤癌进行定量可视化和检测。
J Vis Exp. 2011 May 5(51):2679. doi: 10.3791/2679.
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A heat transfer model of skin tissue for the detection of lesions: sensitivity analysis.皮肤组织病变检测的传热模型:敏感性分析。
Phys Med Biol. 2010 Oct 7;55(19):5933-51. doi: 10.1088/0031-9155/55/19/020. Epub 2010 Sep 21.
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Motion artifact reduction in breast dynamic infrared imaging.乳腺动态红外成像中的运动伪影减少
IEEE Trans Biomed Eng. 2009 Mar;56(3):903-6. doi: 10.1109/TBME.2008.2005584. Epub 2008 Sep 16.
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The template update problem.模板更新问题。
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Evaluation of feature-based registration in dynamic infrared imaging for breast cancer diagnosis.用于乳腺癌诊断的动态红外成像中基于特征的配准评估。
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