Fuller-Thomson Esme, Battiston Marla, Gadalla Tahany M, Shaked Yael, Raza Ferrah
Factor-Inwentash Faculty of Social Work, University of Toronto, Toronto, ON, Canada M5S 1V4.
Depress Res Treat. 2014;2014:828965. doi: 10.1155/2014/828965. Epub 2014 Jan 27.
Individuals with arthritis are vulnerable to depression. In this study, we calculated time to remission from depression in a representative community-based sample of depressed Canadians with arthritis who were followed for 12 years. We conducted secondary analysis of a longitudinal panel study, the National Population Health Survey, which was begun in 1994/95 and has included biennial assessment of depression since that time. Our analysis focused on a total of 216 respondents with arthritis who were depressed at baseline. The mean time to remission from depression was calculated using the Kaplan-Meier procedure and compared across categories of each of the potential predictors. The percentage of those no longer screening positive for depression was calculated at two years after baseline. At two years after baseline, 71% of the sample had achieved remission from depression. Time to remission was significantly longer for those depressed adults who were under the age of 55, those who reported more chronic pain at baseline, those with comorbid migraine, and those who experienced childhood physical abuse or parental addictions. These findings highlight the importance of screening for these factors to improve the targeting of interventions to depressed patients with arthritis.
患有关节炎的人易患抑郁症。在本研究中，我们计算了以社区为基础的患有关节炎的加拿大抑郁症患者代表性样本中抑郁症缓解所需的时间，这些患者被随访了12年。我们对一项纵向面板研究——全国人口健康调查进行了二次分析，该调查始于1994/1995年，自那时起每两年对抑郁症进行一次评估。我们的分析集中在总共216名基线时患有抑郁症的患有关节炎的受访者身上。使用Kaplan-Meier方法计算抑郁症缓解的平均时间，并在每个潜在预测因素的类别之间进行比较。在基线后两年计算不再筛查出抑郁症呈阳性的患者百分比。在基线后两年，71%的样本实现了抑郁症缓解。55岁以下的抑郁症成年人、基线时报告有更多慢性疼痛的人、患有合并偏头痛的人以及经历过童年身体虐待或父母有成瘾问题的人，其缓解时间明显更长。这些发现突出了筛查这些因素对于改善针对患有关节炎的抑郁症患者干预措施的针对性的重要性。
