喉咙痛。
Sore throat.
作者信息
Kenealy Tim
机构信息
Department of General Practice and Primary Health Care, University of Auckland, Auckland, New Zealand.
出版信息
BMJ Clin Evid. 2014 Mar 4;2014:1509.
INTRODUCTION
About 10% of people present to primary healthcare services with sore throat each year. The causative organisms of sore throat may be bacteria (most commonly Streptococcus) or viruses (typically rhinovirus), although it is difficult to distinguish bacterial from viral infections clinically.
METHODS AND OUTCOMES
We conducted a systematic review and aimed to answer the following clinical question: What are the effects of interventions to reduce symptoms of acute infective sore throat? We searched Medline, Embase, The Cochrane Library, and other important databases up to September 2013 (Clinical Evidence reviews are updated periodically; please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA).
RESULTS
We found 6 studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions.
CONCLUSIONS
In this systematic review, we present information relating to the effectiveness and safety of the following interventions: antibiotics, corticosteroids, non-steroidal anti-inflammatory drugs, and paracetamol.
引言
每年约有10%的人因喉咙痛前往基层医疗服务机构就诊。喉咙痛的致病微生物可能是细菌（最常见的是链球菌）或病毒（通常是鼻病毒），不过临床上很难区分细菌感染和病毒感染。
方法与结果
我们进行了一项系统评价，旨在回答以下临床问题：减轻急性感染性喉咙痛症状的干预措施有哪些效果？我们检索了截至2013年9月的Medline、Embase、Cochrane图书馆及其他重要数据库（《临床证据》综述会定期更新；请查看我们的网站获取本综述的最新版本）。我们纳入了来自美国食品药品监督管理局（FDA）和英国药品和医疗产品监管局（MHRA）等相关组织的危害警示。
结果
我们发现6项研究符合我们的纳入标准。我们对干预措施的证据质量进行了GRADE评估。
结论
在本系统评价中，我们提供了以下干预措施的有效性和安全性相关信息：抗生素、皮质类固醇、非甾体抗炎药和对乙酰氨基酚。
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