一种靶向治疗诊断用铂（IV）前药，其包含具有聚集诱导发光（AIE）特性的发光团，用于原位监测药物活化。
A targeted theranostic platinum(IV) prodrug containing a luminogen with aggregation-induced emission (AIE) characteristics for in situ monitoring of drug activation.
作者信息
Yuan Youyong, Chen Yilong, Tang Ben Zhong, Liu Bin
机构信息
Department of Chemical and Biomolecular Engineering, National University of Singapore, 4 Engineering Drive 4, Singapore117576.
出版信息
Chem Commun (Camb). 2014 Apr 14;50(29):3868-70. doi: 10.1039/c3cc49516g. Epub 2014 Mar 4.
PMID:24589580
Abstract
A targeted theranostic platinum(IV) prodrug based on a luminogen with aggregation-induced emission (AIE) characteristics was developed for selective and real-time monitoring of drug activation in situ.
摘要
基于具有聚集诱导发光（AIE）特性的发光团构建了一种靶向诊疗铂（IV）前药，用于原位选择性实时监测药物激活。
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