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非骨水泥羟基磷灰石涂层双极与骨水泥股骨柄治疗股骨颈骨折的对比:一项病例对照研究。

A comparison of the use of uncemented hydroxyapatite-coated bipolar and cemented femoral stems in the treatment of femoral neck fractures: a case-control study.

机构信息

Department of Orthopaedic Surgery, Royal Infirmary of Edinburgh, Old Dalkeith Road, Edinburgh, EH16 4SA, UK.

出版信息

Bone Joint J. 2014 Mar;96-B(3):299-305. doi: 10.1302/0301-620X.96B3.32271.

DOI:10.1302/0301-620X.96B3.32271
PMID:24589782
Abstract

We performed a case-control study to compare the rates of further surgery, revision and complications, operating time and survival in patients who were treated with either an uncemented hydroxyapatite-coated Corail bipolar femoral stem or a cemented Exeter stem for a displaced intracapsular fracture of the hip. The mean age of the patients in the uncemented group was 82.5 years (53 to 97) and in the cemented group was 82.7 years (51 to 99) We used propensity score matching, adjusting for age, gender and the presence or absence of dementia and comorbidities, to produce a matched cohort receiving an Exeter stem (n = 69) with which to compare the outcome of patients receiving a Corail stem (n = 69). The Corail had a significantly lower all-cause rate of further surgery (p = 0.016; odds ratio (OR) 0.18, 95% CI 0.04 to 0.84) and number of hips undergoing major further surgery (p = 0.029; OR 0.13, 95% CI 0.01 to 1.09). The mean operating time was significantly less for the Corail group than for the cemented Exeter group (59 min [12 to 136] vs 70 min [40 to 175], p = 0.001). The Corail group also had a lower risk of a peri-prosthetic fracture (p = 0.042; OR 0.19, 95% CI 0.01 to 1.42) . There was no difference in the mortality rate between the groups. There were significantly fewer complications in the uncemented group, suggesting that the use of this stem would result in a decreased rate of morbidity in these frail patients. Whether this relates to an improved functional outcome remains unknown.

摘要

我们进行了一项病例对照研究,比较了接受非骨水泥羟基磷灰石涂层 Corail 双极股骨柄或骨水泥 Exeter 柄治疗髋关节囊内移位性骨折的患者进一步手术、翻修和并发症、手术时间和生存率的发生率。非骨水泥组患者的平均年龄为 82.5 岁(53 至 97 岁),骨水泥组为 82.7 岁(51 至 99 岁)。我们使用倾向评分匹配,调整年龄、性别以及是否存在痴呆和合并症,生成了一个接受 Exeter 柄治疗的匹配队列(n = 69),并将其与接受 Corail 柄治疗的患者的结果进行比较(n = 69)。Corail 组全因进一步手术的发生率明显较低(p = 0.016;比值比(OR)0.18,95%可信区间 0.04 至 0.84),需要进行重大进一步手术的髋关节数量也较少(p = 0.029;OR 0.13,95%可信区间 0.01 至 1.09)。Corail 组的手术时间明显短于骨水泥 Exeter 组(59 分钟 [12 至 136] 与 70 分钟 [40 至 175],p = 0.001)。Corail 组假体周围骨折的风险也较低(p = 0.042;OR 0.19,95%可信区间 0.01 至 1.42)。两组死亡率无差异。非骨水泥组并发症明显较少,这表明使用这种柄会降低这些脆弱患者的发病率。这是否与改善功能结果有关尚不清楚。

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