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麻醉剂对小型猪纤溶活性的影响。

Influence of anaesthetics on the fibrinolytic activity in minipigs.

作者信息

Klöcking H P, Sedlarik K

机构信息

Institute of Pharmacology and Toxicology, Medical Academy Erfurt, GDR.

出版信息

Folia Haematol Int Mag Klin Morphol Blutforsch. 1988;115(1-2):132-5.

PMID:2459007
Abstract

The activator of the fibrinolytic system measured in minipigs may be profoundly influenced by ether and halothane. Hexobarbital anaesthesia is recommended for studies where effects of fibrinolysis have to be measured. "Fibrinolytic shutdown" during anaesthesia may be prevented by prophylactic administration of a plasminogen activator releasing agent (pentosan polysulphate).

摘要

小型猪体内所测得的纤溶系统激活剂可能会受到乙醚和氟烷的显著影响。对于必须测量纤溶作用效果的研究,推荐使用己巴比妥麻醉。麻醉期间的“纤溶停滞”可通过预防性给予纤溶酶原激活剂释放剂(戊聚糖多硫酸盐)来预防。

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