上皮黏附连接
Epithelial adhesive junctions.
作者信息
Capaldo Christopher T, Farkas Attila E, Nusrat Asma
机构信息
Epithelial Pathobiology Research Unit, Department of Pathology, Emory University 615 Michael Street, Atlanta, GA 30322 USA.
出版信息
F1000Prime Rep. 2014 Jan 2;6:1. doi: 10.12703/P6-1. eCollection 2014.
Epithelial adhesive cell-to-cell contacts contain large, plasma membrane-spanning multiprotein aggregates that perform vital structural and signaling functions. Three prominent adhesive contacts are the tight junction, adherens junction, and the desmosome. Each junction type has unique cellular functions and a complex molecular composition. In this review, we comment on recent and exciting advances in our understanding of junction composition and function.
上皮细胞间的黏附连接包含大型的、跨质膜的多蛋白聚集体，这些聚集体执行重要的结构和信号功能。三种主要的黏附连接是紧密连接、黏着连接和桥粒。每种连接类型都具有独特的细胞功能和复杂的分子组成。在本综述中，我们对我们在连接组成和功能理解方面的最新且令人兴奋的进展进行评论。
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