van Delft K, Thakar R, Sultan A H, Schwertner-Tiepelmann N, Kluivers K
Urogynaecology Unit, Department of Obstetrics and Gynaecology, Croydon University Hospital, Croydon, UK.
BJOG. 2014 Aug;121(9):1155-63; discussion 1163. doi: 10.1111/1471-0528.12676. Epub 2014 Mar 5.
To establish the incidence of levator ani muscle (LAM) avulsion in primiparous women and to develop a clinically applicable risk prediction model.
Observational longitudinal cohort study.
District General University Hospital, United Kingdom.
Nulliparous women at 36 weeks of gestation and 3 months postpartum.
Four-dimensional transperineal ultrasound was performed during both visits. Tomographic ultrasound imaging at maximum contraction was used to diagnose no, minor or major LAM avulsion. A risk model was developed using multivariable ordinal logistic regression.
Incidence of LAM avulsion and its risk factors.
Of 269 women with no antenatal LAM avulsion 71% (n = 191) returned postpartum. No LAM avulsion was found after caesarean section (n = 48). Following vaginal delivery the overall incidence of LAM avulsion was 21.0% (n = 30, 95% confidence interval [95% CI] 15.1-28.4). Minor and major LAM avulsion were diagnosed in 4.9% (n = 7, 95% CI 2.2-9.9) and 16.1% (n = 23, 95% CI 10.9-23.0), respectively. Risk factors were obstetric anal sphincter injuries (odds ratio [OR] 4.4, 95% CI 1.6-12.1), prolonged active second stage of labour per hour (OR 2.2, 95% CI 1.4-3.3) and forceps delivery (OR 6.6, 95% CI 2.5-17.2). A risk model and nomogram were developed to estimate a woman's individual risk: three risk factors combined revealed a 75% chance of LAM avulsion.
Twenty-one percent of women sustain LAM avulsion during their first vaginal delivery. Our risk model and nomogram are novel tools to estimate individual chances of LAM avulsion. We can now target postnatal women at risk of sustaining a LAM avulsion.
确定初产妇肛提肌(LAM)撕裂的发生率,并建立一个临床适用的风险预测模型。
观察性纵向队列研究。
英国地区综合大学医院。
妊娠36周和产后3个月的未产妇。
两次访视期间均进行经会阴四维超声检查。在最大收缩时进行断层超声成像,以诊断无、轻度或重度LAM撕裂。使用多变量有序逻辑回归建立风险模型。
LAM撕裂的发生率及其危险因素。
269例产前无LAM撕裂的女性中,71%(n = 191)产后回访。剖宫产术后未发现LAM撕裂(n = 48)。阴道分娩后,LAM撕裂的总体发生率为21.0%(n = 30,95%置信区间[95%CI]15.1 - 28.4)。轻度和重度LAM撕裂的诊断率分别为4.9%(n = 7,95%CI 2.2 - 9.9)和16.1%(n = 23,95%CI 10.9 - 23.0)。危险因素包括产科肛门括约肌损伤(比值比[OR]4.4,95%CI 1.6 - 12.1)、活跃期第二产程每延长1小时(OR 2.2,95%CI 1.4 - 3.3)和产钳助产(OR 6.6,95%CI 2.5 - 17.2)。建立了一个风险模型和列线图来估计女性的个体风险:三个危险因素综合起来显示LAM撕裂的几率为75%。
21%的女性在首次阴道分娩时发生LAM撕裂。我们的风险模型和列线图是估计LAM撕裂个体几率的新工具。现在我们可以针对有发生LAM撕裂风险的产后女性。