Department of Clinical Sciences, Karolinska Institutet, Danderyd Hospital, Stockholm, Sweden.
Department of Women's Health, Danderyd Hospital, 18288, Stockholm, Sweden.
Sci Rep. 2022 May 5;12(1):7315. doi: 10.1038/s41598-022-11346-x.
The objective was to investigate the effect of delivery mode on anal incontinence 1-2 years after delivery in primiparous women with prolonged second stage of labor. This population-based cohort and questionnaire study performed in Stockholm Region, Sweden, included 1302 primiparous women with a second stage ≥ 3 h from December 1st, 2017 through November 30th, 2018. Background characteristics and outcome data were retrieved from computerized records. Questionnaires based on Wexner score were distributed 1-2 years after delivery. Risk of anal incontinence, defined as Wexner score ≥ 2, was calculated using logistic regression and presented as crude and adjusted odds ratios (OR and aOR) with 95% confidence intervals (CI). Compared with cesarean section, vacuum extraction was associated with anal incontinence (aOR 2.25, 95% CI 1.21-4.18) while spontaneous delivery was not (aOR 1.55, 95% CI 0.85-2.84). Anal incontinence was independently associated with obstetric anal sphincter injuries (aOR 2.03, 95% CI 1.17-3.5) and 2nd degree perineal tears (aOR 1.36, 95% CI 1.03-1.81) compared with no or 1st degree perineal tear. Obstetric anal sphincter injury at vacuum extraction inferred the highest risk of anal incontinence (aOR 4.06, 95% CI 1.80-9.14), compared with cesarean section. Increasing duration of the prolonged second stage did not affect the risk.
目的在于调查初产妇第二产程延长对产后 1-2 年肛门失禁的影响。该研究是基于人群的队列和问卷调查,在瑞典斯德哥尔摩地区进行,纳入了 2017 年 12 月 1 日至 2018 年 11 月 30 日期间 1302 名第二产程≥3 小时的初产妇。背景特征和结局数据来自计算机记录,产后 1-2 年通过问卷调查收集。肛门失禁的风险定义为 Wexner 评分≥2,使用逻辑回归计算,以比值比(OR)和调整比值比(aOR)及其 95%置信区间(CI)表示。与剖宫产相比,真空吸引分娩与肛门失禁相关(aOR 2.25,95%CI 1.21-4.18),而自然分娩无此相关性(aOR 1.55,95%CI 0.85-2.84)。与无会阴撕裂或 1 度会阴撕裂相比,产科肛门括约肌损伤(aOR 2.03,95%CI 1.17-3.5)和 2 度会阴撕裂(aOR 1.36,95%CI 1.03-1.81)与肛门失禁独立相关。与剖宫产相比,真空吸引分娩时发生产科肛门括约肌损伤的肛门失禁风险最高(aOR 4.06,95%CI 1.80-9.14)。第二产程延长的持续时间增加不会影响风险。