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加巴喷丁:它会被滥用吗?

Gabapentin: can it be misused?

作者信息

Howland Robert H

出版信息

J Psychosoc Nurs Ment Health Serv. 2014 Jan;52(1):12-5. doi: 10.3928/02793695-20131213-01.

Abstract

Gabapentin, a gamma-aminobutyric acid analog drug, appears to be safe and efficacious for the treatment of alcohol dependence. Gabapentin is not a controlled drug, but there are anecdotal reports of its misuse and abuse as well as reports of withdrawal symptoms associated with abrupt discontinuation. The risk of gabapentin misuse is inconsistent, the magnitude of the risk is small, and the risk is not comparable to the much higher risks associated with alcohol use; benzodiazepine, opioid, and stimulant drug use; or illicit drug use. Reports of gabapentin misuse are not unique to this drug, as misuse of prescription medications not typically considered "drugs of abuse" can also occur.

摘要

加巴喷丁是一种γ-氨基丁酸类似物药物,似乎对治疗酒精依赖安全有效。加巴喷丁不是管制药物,但有关于其滥用和误用的传闻报道,以及与突然停药相关的戒断症状报告。加巴喷丁误用的风险并不一致,风险程度较小,且该风险与饮酒、使用苯二氮䓬类药物、阿片类药物和兴奋剂药物或非法药物所带来的高得多的风险不可相提并论。加巴喷丁误用的报道并非该药物所独有,因为通常不被视为“滥用药物”的处方药也可能被误用。

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