Kondo Takashi, Kusunoki Shinji, Kuroda Masahiko, Kawamoto Masashi
Department of Anesthesiology and Critical Care, Hiroshima University Hospital, Hiroshima, Japan.
Department of Anesthesiology and Critical Care, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan.
Hiroshima J Med Sci. 2013 Dec;62(4):91-4.
Liver transplantation with hypertrophic obstructive cardiomyopathy is associated with acute hemodynamic changes, which can exacerbate left ventricular outflow tract obstruction during surgery. Therefore, selection of general anesthetic agents is important, as most can result in hemodynamic instability by reducing systemic vascular resistance and blood pressure. We report successful anesthetic management in a case of living donor liver transplantation with hypertrophic obstructive cardiomyopathy using ketamine, propofol, and fentanyl to avoid vasodilation by anesthetic agents. In addition, landiolol, phenylephrine, and low-dose dopamine were administered to prevent left ventricular outflow tract obstruction, and were found to be effective for improving acute hemodynamic changes during surgery. In the case of this patient, the combination of transesophageal echocardiography and a pulmonary artery catheter was beneficial for intraoperative hemodynamic monitoring.