Phillips Siobhan M, Alfano Catherine M, Perna Frank M, Glasgow Russell E
Authors' Affiliations: Office of Cancer Survivorship; Implementation Sciences Team; Health Behaviors Research Branch, Behavioral Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Rockville, MD; and Colorado Health Outcomes Program, University of Colorado, Boulder, Colorado.
Cancer Epidemiol Biomarkers Prev. 2014 May;23(5):687-99. doi: 10.1158/1055-9965.EPI-13-1355. Epub 2014 Mar 5.
Physical activity has been deemed safe and effective in reducing many negative side effects of treatment for cancer survivors and promoting better overall health. However, most of this research has focused on highly controlled randomized trials and little of this research has been translated into care or policy for survivors. The purpose of the present article is to present a research agenda for the field to accelerate the dissemination and implementation of empirically supported physical activity interventions into care. We provide rationale for the role of basic, behavioral, clinical implementation, and population scientists in moving this science forward and call for a more coordinated effort across different phases of research. In addition, we provide key strategies and examples for ongoing and future studies using the RE-AIM (reach, efficacy/effectiveness, adoption, implementation, and maintenance) framework and pose recommendations for collaborations between researchers and stakeholders to enhance the integration of this research into policy and practice. Overall, we recommend that physical activity and cancer survivorship research use additional study designs, include relevant stakeholders, and be more collaborative, integrated, contextual, and representative in terms of both setting and participants.
体育活动已被认为在减少癌症幸存者治疗的许多负面副作用以及促进整体健康改善方面是安全有效的。然而，大部分此类研究都集中在高度受控的随机试验上，而且很少有研究成果转化为针对幸存者的护理或政策。本文的目的是为该领域提出一个研究议程，以加速将经验证有效的体育活动干预措施传播并实施到护理中。我们阐述了基础科学家、行为科学家、临床实施科学家和群体科学家在推动这一科学发展中的作用的理论依据，并呼吁在研究的不同阶段进行更协调的努力。此外，我们提供了使用RE-AIM（覆盖范围、疗效/效果、采用、实施和维持）框架进行当前和未来研究的关键策略及示例，并就研究人员与利益相关者之间的合作提出建议，以加强将该研究整合到政策和实践中。总体而言，我们建议体育活动与癌症幸存者研究采用更多的研究设计，纳入相关利益相关者，并在研究背景和参与者方面更具协作性、综合性、情境性和代表性。
