Kumar Harsh, Buch Archana C, Sawlani Vinay M, Chandanwale Shirish S
Department of Pathology, Padmashree Dr. DY Patil Medical College, Pune, Maharashtra, India.
Adv Biomed Res. 2014 Jan 9;3:33. doi: 10.4103/2277-9175.124685. eCollection 2014.
Osteosarcoma is the most common primary malignant tumor of the skeleton involving predominantly metaphysis of the long bones. Diaphyseal osteosarcoma is a rare form, which accounts for approximately 10% of all cases of osteosarcomas. Osteosarcoma contains a family of lesions with considerable diversity in histologic features and grade. We present a case of a 29-year-old male with diaphyseal osteosarcoma of the left tibia, who presented with pain and swelling over middle one-third of the left leg. The biopsy of the lesion revealed varied histomorphologic features in a small tissue studied. This prompted us to report the various histologic patterns of osteosarcoma.
骨肉瘤是骨骼最常见的原发性恶性肿瘤，主要累及长骨的干骺端。骨干骨肉瘤是一种罕见类型，约占所有骨肉瘤病例的10%。骨肉瘤包含一系列组织学特征和分级差异很大的病变。我们报告一例29岁男性左胫骨骨干骨肉瘤患者，其表现为左腿中三分之一处疼痛和肿胀。病变活检显示，在研究的小块组织中具有多种组织形态学特征。这促使我们报告骨肉瘤的各种组织学模式。
