Ahmad Iftikhar
Department of ENT, Head and Neck Surgery, Postgraduate Medical Institute, Lady Reading Hospital, Peshawar, Pakistan.
J Pak Med Assoc. 2013 Sep;63(9):1094-7.
To determine the frequency of tuberculous lymphadenitis in patients with cervical lymphadenopathy, and to determine the association of tuberculous lymphadenitis with body mass index.
The descriptive cross-sectional study was conducted at the Department of ear, nose, throat (ENT), Head and Neck Surgery, Post Graduate Medical Institute, Lady Reading Hospital Peshawar, from March, 2010 to February 2011 included 101 patients with enlarged cervical lymph nodes fulfilling the inclusion criteria. Tuberculosis was diagnosed in cervical lymph nodes by fine needle aspiration and open biopsies where needed. Data was collected on a pre-designed proforma and was analysed by SPSS 11.
The study comprised 101 cases with cervical lymphadenopathy: 63 (62.37%) females and 38 (37.62%) males, with a female:male ratio of 1.65:1 .The age of the patients ranged from 03-67 years with a mean of 32.56 +/- 13.49 years. Most of patients (n = 77; 76.23%) were from lower socioeconomic group and had low body mass index. The main complaint of these patients was fever (n = 35; 34.65%). Extrapulmonary tuberculosis was the commonest diagnosis in cervical lymphadenopathy accounting for 7 6(75.24%), while reactive hyperplastic lymphadenopathy (n = 11; 10.89%) was the next common finding. Rare diseases diagnosed in cervical lymph nodes were Hodgkin's disease 2 (1.98%), Non-Hodgkin's lymphoma 2 (1.98%), and 1 (0.99%) case of Kikuchi's disease. The tuberculous cervical lymphadenopathy was significantly associated with low body mass index (p < 0.0001).
Tuberculous cervical lymphadenopathy is a common disease in our society. It is more common in young poor females with low body mass index. Therefore, it is important to have a high index of suspicion for diagnosing tubercular lymphadenopathy.
确定颈淋巴结病患者中结核性淋巴结炎的发生率，并确定结核性淋巴结炎与体重指数之间的关联。
2010年3月至2011年2月，在白沙瓦市莱迪·雷丁医院研究生医学研究所耳鼻喉科（ENT）及头颈外科进行了描述性横断面研究，纳入了101例符合纳入标准的颈部淋巴结肿大患者。必要时通过细针穿刺和开放性活检诊断颈部淋巴结结核。数据通过预先设计的表格收集，并使用SPSS 11进行分析。
该研究包括101例颈淋巴结病患者：女性63例（62.37%），男性38例（37.62%），女性与男性比例为1.65:1。患者年龄范围为3至67岁，平均年龄为32.56±13.49岁。大多数患者（n = 77；76.23%）来自社会经济地位较低的群体，体重指数较低。这些患者的主要主诉是发热（n = 35；34.65%）。肺外结核是颈淋巴结病最常见的诊断，占76例（75.24%），而反应性增生性淋巴结病（n = 11；10.89%）是第二常见的发现。在颈部淋巴结中诊断出的罕见疾病有霍奇金病2例（1.98%）、非霍奇金淋巴瘤2例（1.98%）和菊池病1例（0.99%）。结核性颈淋巴结炎与低体重指数显著相关（p < 0.0001）。
结核性颈淋巴结炎在我们的社会中是一种常见疾病。在体重指数较低的年轻贫困女性中更为常见。因此，对结核性淋巴结炎的诊断保持高度怀疑指数很重要。
