Golshan Mohammad, Hossein Nematizadeh
Department of Paediatric, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran.
J Pak Med Assoc. 2013 Sep;63(9):1117-9.
To compare the extraction time and infection rate of umbilical cord by applying ethanol, humanmilk or dry care.
The parallel single-blinded randomised clinical trial was performed on 300 neonates at Shahid Sadougi University of Medical Sciences and Health Service, Yazd, Iran, between March and September 2010. The neonates were divided into three random but numerically equal groups. Each group was assigned the application of ethanol or mother's milk or to keep the stump dry. The neonates were visited on the 3rd and the 7th day after birth and follow-up was maintained telephonically until umbilical separation. Umbilical separation time and umbilical local infection frequency were considered as the study outcome, which was compared among the three groups according to age, gender and delivery type of the neonates.
Umbilical separation time in neonates of the human milk group had significant difference with the ethanol group (p=0.0001) and drying groups (p = 0.003). Frequency of omphalitis had no significant difference among the three groups.
Topical usage of human milk on umbilical cord stamp decreased separation time and incidence rate of omphalitis.
比较应用乙醇、母乳或干燥护理法处理脐带的提取时间和感染率。
2010年3月至9月间，在伊朗亚兹德沙希德·萨杜吉医科大学卫生服务中心对300名新生儿进行了平行单盲随机临床试验。将新生儿随机分为三组，每组人数相等。分别对每组新生儿应用乙醇、母乳或保持脐带残端干燥。在出生后第3天和第7天对新生儿进行访视，并通过电话进行随访，直至脐带脱落。将脐带脱落时间和脐带局部感染频率作为研究结果，根据新生儿的年龄、性别和分娩方式在三组之间进行比较。
母乳组新生儿的脐带脱落时间与乙醇组（p = 0.0001）和干燥组（p = 0.003）有显著差异。三组之间脐炎的发生率无显著差异。
在脐带残端局部使用母乳可缩短脐带脱落时间并降低脐炎发生率。
