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[The action of gramicidin S on the ionic permeability of bilayer lipid membranes].

作者信息

Korolev P N, Bulgakova V G, Polin A N, Korolev N P, Mil'gram V D

出版信息

Nauchnye Doki Vyss Shkoly Biol Nauki. 1988(7):31-5.

PMID:2460145
Abstract

The effect of cyclic decapeptide of gramicidin S on electrical conductivity of bilayer lipid membranes has been studied. The integral conductivity of bilayer has been shown to increase with the growth of antibiotic concentration. The integral conductivity increase occurs as series of conductivity discrete leaps, differing in amplitude from fluctuations of conductivity caused by linear gramicidins. In the series of selectivity of bilayer membranes for cations of alkaline metals the rubidium ion is before the cesium ion. This is the only difference between this series and the series of relative ionic mobility series of cations of alkaline metals in water solutions.

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